[LL 804] OCTOBER 2017 Sub. Code: 3804
PHARM. D DEGREE EXAMINATION
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(2009-2010 Regulation)
FIRST YEAR
PAPER IV - PHARMACEUTICAL ORGANIC CHEMISTRY
Q.P. Code: 383804
Time : Three hours Maximum : 70 Marks
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- Elaborate on: (4 x 10 =40) - What do you understand by the term Aliphatic Nucleophilic substitution reactions? Explain the reaction, mechanism, kinetic, stereochemistry and factors influencing SN1 reactions.
- Write in detail the mechanism of free radical halogenations of Methane. Discuss its thermodynamics.
- Discuss the reaction, mechanism and its synthetic application of: - Perkins condensation
- Cannizaro reaction.
 
- Discuss the mechanism of the following: - Nitration of Benzene
- Chlorination of Propene
 
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- Write notes on: (6x5=30) - Acid base theory.
- Write a note on acidity of carboxylic acid.
- Classification and stability of free radicals.
- Conversion of carboxylic acid to acid chloride and amide.
- Discuss the preparation, assay and uses of Vanillin.
- Oxidation reactions.
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