Pharm D Last 12 Years 2010-2022 Question Papers (1st Year, 2nd Year, 3rd Year, 4th Year and 5th Year)
[LO 804] MAY 2019 Sub. Code: 3804
PHARM. D DEGREE EXAMINATION
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(2009-2010 Regulation)
FIRST YEAR
PAPER IV - PHARMACEUTICAL ORGANIC CHEMISTRY
O.P. Code : 383804
Time : Three hours Maximum : 70 Marks
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I. Elaborate on: (4 x 10 =40)
- Explain the Aliphatic nucleophilic substitution with mechanisms and kinetics involved in the reactions.
- Explain the mechanisms of following name reactions:
a) Benzoin condensation. b) Wittig reaction. - Explain the activating and deactivating O, P, and M directing groups in the aromatic compounds.
- Give an account of acid and base on the basis of Lewis theory and Lowry-Bronsted concept.
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II. Write notes on: (6x5=30)
- Preparation, tests for purity, assay and uses of aspirin.
- Explain the reaction mechanisms of Sandmeyer’s reduction with suitable examples.
- Explain Fries rearrangement and Hofmann rearrangement.
- Add a note on Isomerism.
- What are cycloalkanes? Give example. How are cycloalkanes prepared?
- Polarity of bond and Aprotic solvents.
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