[LD 804] OCTOBER 2013 Sub. Code: 3804
DOCTOR OF PHARMACY (PHARM. D) DEGREE EXAMINATION
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FIRST YEAR
PAPER IV - PHARMACEUTICAL ORGANIC CHEMISTRY
Q.P. Code: 383804
Time: Three Hours Maximum: 70 marks
Answer All questions
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-  Elaborate on: (2x20=40) - Write the Electrophilic addition reactions of alkenes.
- Write about basicity of amines.
 
-  - Explain the mechanisms involved in Elimination reactions.
-  - Aldol Condensation.
- Hoffmann rearrangement.
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II. Write notes on: (10x 3 =30)
- Aliphatic Nucleophilic substitution V.s. Aromatic nucleophilic substitution.
- Fries rearrangement.
-  Write the preparation and medicinal uses of - Vanillin.
- Salicylic acid.
 
- Write any three methods of preparation of carboxylic acids.
-  - Williamsons synthesis.
- Sandmeyer reaction.
 
- 1, 4-addition and 1,2-addition reactions of Dienes.
- Markownikoff’s rule.
- Bayers strain theory.
- SN1 VS. SN2.
- Phase transfer catalysis.
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