Download Pharm D 1st Year 2014 April 383804 Pharmaceutical Organic Chemistry Question Paper

Download Pharm-D (Doctor of Pharmacy) 1st Year (First Year) 2014 April 383804 Pharmaceutical Organic Chemistry Previous Question Paper

[LE 804] APRIL 2014 Sub. Code: 3804
DOCTOR OF PHARMACY (PHARM. D) DEGREE EXAMINATION
FIRST YEAR
PAPER IV ? PHARMACEUTICAL ORGANIC CHEMISTRY
Q.P. Code: 383804
Time: Three Hours Maximum: 70 marks
Answer All questions
I. Elaborate on: (2 x 20 = 40)
1. What are Electrophilic addition reactions? Explain any two reactions in detail.
2. Explain the mechanism and reactions of the following:
a) Claisen condensation.
b) Knoevenagel reaction.
c) Perkin condensation.
d) Kolbe reaction.
II. Write notes on: (10 x 3 = 30)
1. Diel?s alder reaction.
2. Discuss the mechanism and synthetic uses of Aldol condensation.
3. Give an account of acid and base on the basis of Lewis theory.
4. Give an example for free radical halogenation of alkenes with respect to
carbon-carbon double bond acting as a substituent.
5. Write a note on activating and deactivating Ortho, Para and Meta directing groups.
6. Write any two methods of conversion of acid to esters.
7. Riemer ?Tiemann?s reaction.
8. Write any two methods to prepare alkyl halides.
9. Add a note on carbocations.
10. Write the preparation, test for purity, Assay and uses of Saccharin.

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