Download Pharm D 1st Year 2014 Oct 383804 Pharmaceutical Organic Chemistry Question Paper

Download Pharm-D (Doctor of Pharmacy) 1st Year (First Year) 2014 Oct 383804 Pharmaceutical Organic Chemistry Previous Question Paper

[LF 804] OCTOBER 2014 Sub. Code: 3804
DOCTOR OF PHARMACY (PHARM. D) DEGREE EXAMINATION
(2009-2010 Regulation)
FIRST YEAR
PAPER IV ? PHARMACEUTICAL ORGANIC CHEMISTRY
Q.P. Code: 383804
Time: Three Hours Maximum: 70 marks
Answer All questions
I. Elaborate on: (4 x 10 = 40)
1. Discuss the reaction, mechanism of Nucleophilic aromatic substitution.
2. Briefly discuss Stereochemistry of SN1 and SN2 reaction.
How rearrangement take place in carbocation in Nuclophilic aliphatic substitution.
3. Mention the reaction of conversion of acid to:
a) Amide.
b) Acid chloride.
c) Esters.
d) Anhydride.
4. Explain the following reaction with mechanism:
a) Diazotisation and coupling.
b) Aldol condensation.
II. Write notes on: (6 x 5 = 30)
1. Explain the addition reaction of conjugated dienes.
2. Write the structure, preparation, Assay and chemical uses of Sodium lauryl sulphate.
3. Explain the Wittig reaction with mechanisms.
4. Additions of carbine.
5. Orbital picture of Allyl radical.
6. Explain the mechanism of E1 and E2 reaction.

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