Pharm D Last 12 Years 2010-2022 Question Papers (1st Year, 2nd Year, 3rd Year, 4th Year and 5th Year)
PHARM. D DEGREE EXAMINATION (2009-2010 Regulation)
FIRST YEAR
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PAPER IV - PHARMACEUTICAL ORGANIC CHEMISTRY
O.P. Code : 383804
Time : Three hours Maximum : 70 Marks
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I. Elaborate on: (4 x 10 =40)
- Discuss in detail about the mechanism and thermodynamics of free radical halogenations of methane.
- Briefly explain the mechanism and kinetics involved in nucleophilic unimolecular and bimolecular reactions.
- Explain Kolbe’s reaction and Fries rearrangement.
- Discuss the 1, 2 addition and 1, 4 addition reactions of conjugated dienes.
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II. Write notes on: (6x5=30)
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- Write a brief note about the basicity of amines.
- Briefly explain Bayer’s strain theory.
- Write a note on Resonance.
- Write the test for purity, assay and medicinal uses of salicylic acid.
- Explain Markownikoff rule with example.
- Explain the acid base on the basis of Lowry-Bronsted concept.
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