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[LA 810] APRIL 2012 Sub. Code: 3810
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DOCTOR OF PHARMACY (PHARM. D) DEGREE EXAMINATION
(2009-2010 Regulation)
SECOND YEAR
PAPER IV - PHARMACOLOGY -1
O.P. Code: 383810
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Time: Three Hours Maximum: 100 marks
Answer ALL questions in the same order.
I. Elaborate on : Pages Time Marks
(Max.) (Max.) (Max.)
1. Describe the types of cholinoceptors (4). 17 40 min. 20
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Classify the cholinergic agonist (8).
Write briefly about its pharmacological actions (8).
2. Define Parkinsonism (2). 17 40 min. 20
Classify the antiparkinsonian drugs (4).
Write the mechanism of action (6),
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drug interactions(4) and uses of dopamine precursors (4).
II. Write notes on :
1. Write briefly about the phases involved in Bio-transformation. 4 10min. 6
2. Explain the stages of general anaesthesia. 4 10min. 6
3. Mention the therapeutic uses of digitalis in the case of
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congestive heart failure. 4 10min. 6
4. Explain the Dopamine theory of Schizophrenia. 4 10min. 6
5. Classify Central Nervous System stimulants(3) and
Write the mechanism of action of psychostimulants. (3) 4 10min. 6
6. Write the clinical uses of Nitrates in angina. 4 10min. 6
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7. Write a note on HMG-CoA reductase inhibitors. 4 10min. 6
8. Describe the various routes of drug administration. 4 10min. 6
9. Write the synthesis, storage and metabolism of
5-Hydroxytryptamine 4 10min. 6
10. Write the pharmacological actions of COX-2 inhibitors 4 10min. 6
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