PHARM. D DEGREE EXAMINATION
(2009-2010 Regulation)
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THIRD YEAR
PAPER V - MEDICINAL CHEMISTRY
Q.P. Code : 383817
Time : Three hours Maximum : 70 Marks
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I. Elaborate on: (4 x 10 =40)
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- Write a brief account on hydrophobic parameters and spatial descriptors involved in a QSAR.
- Classify Antifungal agents with suitable examples. Discuss the chemistry, structure and mechanism of any two antifungal antibiotics.
- Define and classify anti-tubercular agents. Give the synthesis of any two drugs with mechanism of action from antitubercular agents.
- Discuss the SAR of thiazide diuretics.
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II. Write notes on: (6x5=30)
- Discuss briefly about Anticoagulants drugs with suitable examples.
- Write a note on HIV Protease inhibitors.
- Write a short note on anti-anginal agents.
- Write a short note on steroidal sex hormones.
- Enumerate about Macrolide antibiotics.
- Write a note on sulpha drugs used burn therapy.
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