Pharm D Last 12 Years 2010-2022 Question Papers (1st Year, 2nd Year, 3rd Year, 4th Year and 5th Year)
[LG 817] APRIL 2015 Sub. Code: 3817
DOCTOR OF PHARMACY (PHARM. D) DEGREE EXAMINATION
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(2009-2010 Regulation)
THIRD YEAR
PAPER V — MEDICINAL CHEMISTRY
Q.P. Code: 383817
Time: Three Hours Maximum: 70 marks
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Answer All questions
- Elaborate on: (4 x10=40)
- Classify diuretics.
Explain the mechanism of action and structure of any one drug from each class. - Write a brief account on the electronic & steric parameters involved in a QSAR study.
- Classify semisynthetic pencillins.
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Enumerate the mechanism of action and SAR of pencillins. - a) Classify sulphonamides.
Briefly discuss the mechanism of action and SAR of sulphonamides.
b) Enumerate the general synthesis of sulfonamides.
- Classify diuretics.
- Write notes on: (6x5=30)
- Discuss the life cycle of malarial parasite.
- Describe the mechanism of action of.
(a) Polyene antifungals (b).Allylamine antifungals. - Write a note on solid phase synthesis in combinatorial chemical library synthesis.
- Discuss briefly on agents used for hyperthyroidism and write the structure of any two drugs.
- Write a note on adrenocorticoids.
- Give the structure and uses of
(a) Chloroquine (b) Clonidine.
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