Download Pharm D 4th Year 2015 April 383823 Biopharmaceutics And Pharmacokinetics Question Paper

Download Pharm-D (Doctor of Pharmacy) 4th Year (Fourth Year) 2015 April 383823 Biopharmaceutics And Pharmacokinetics Previous Question Paper

[LG 823] APRIL 2015 Sub. Code: 3823
DOCTOR OF PHARMACY (PHARM. D / POST BACCALAUREATE)
DEGREE EXAMINATION
(2009-2010 Regulation)
FOURTH YEAR
PAPER V ? BIOPHARMACEUTICS AND PHARMACOKINETICS
Q.P. Code: 383823
Time: Three Hours Maximum: 70 marks
Answer All questions
I. Elaborate on: (4 x 10 = 40)

1. Pharmaceutical factors influencing G.I.T absorption.
2. Nonlinear kinetics ? Causes and estimation of K
m
and V
max
.
3. Bioavailability enhancement through solubility / dissolution rate.
4. Pharmacokinetic analysis of mathematical data.
II. Write notes on: (6 x 5 = 30)
1. Plasma protein bindings.
2. Apparent Volume of distribution.
3. Factors affecting renal excretion.
4. Statistical Moment Theory.
5. Plateau principle.
6. Estimate the creatinine clearance of a 30 year old 70 kg man with serum creatinine
level of 2 mg %. What is the renal function of this patient?

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