PHARM. ‘D’ AND PHARM. ‘D’ (POST BACCALAUREATE) DEGREE EXAMINATION (2009-2010 Regulation) FOURTH YEAR PAPER V — BIOPHARMACEUTICS AND PHARMACOKINETICS
O.P. Code: 383823
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Time : Three hours Maximum : 70 Marks
- Elaborate on : (4 x 10 =40)
- Explain briefly Michaelis — Menten method for estimation of Km and Vmax.
- Define excretion and explain briefly about Renal excretion of drugs.
- Physiological barriers to distribution of Drugs.
- Write briefly about In-vivo — In-vitro correlations and BCS classification.
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- Write notes on : (6x5=30)
- Renal impairment and creatinine clearance.
- Write a note on statistical moment theory.
- Short notes on bioavailability protocol.
- Write the concept and types of clearance.
- Discuss Latin square design in Bioequivalent study.
- What are the formulation factors that affect drug absorption?
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