Pharm D Last 12 Years 2010-2022 Question Papers (1st Year, 2nd Year, 3rd Year, 4th Year and 5th Year)
PHARM. ‘D’ AND PHARM. ‘D’ (POST BACCALAUREATE) DEGREE EXAMINATION (2009-2010 Regulation) FOURTH YEAR PAPER V — BIOPHARMACEUTICS AND PHARMACOKINETICS
Time : Three hours Maximum : 70 Marks
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I. Elaborate on: (4 x 10 =40)
- Explain briefly mechanism of drug absorption in G.I.T.
- Discuss the two compartment open model Intra Venous administration.
- Define Bioavailability. Explain various methods used for determination of Bioavailability.
- Explain the various models of Pharmacokinetic analysis.
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II. Write notes on: (6x5=30)
- What are the objectives and approaches in developing in vitro-in vivo correlation?
- Causes of non-linearity with example.
- Limitations of multi compartmental analysis.
- Discuss the importance of salivary excretion of drugs.
- Discuss in detail regulatory requirements for bioavailability study.
- What are the factors affecting drug dissolution?
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