Download Pharm D 4th Year 2016 Oct 383823 Biopharmaceutics And Pharmacokinetics Question Paper

Download Pharm-D (Doctor of Pharmacy) 4th Year (Fourth Year) 2016 Oct 383823 Biopharmaceutics And Pharmacokinetics Previous Question Paper

[LJ 823] OCTOBER 2016 Sub. Code: 3823

PHARM. ?D? AND PHARM. ?D? (POST BACCALAUREATE)
DEGREE EXAMINATION
(2009-2010 Regulation)
FOURTH YEAR
PAPER V ? BIOPHARMACEUTICS AND PHARMACOKINETICS

Q.P. Code : 383823
Time : Three hours Maximum : 70 Marks

I. Elaborate on: (4 x 10 = 40)

1. Explain briefly mechanism of drug absorption in G.I.T.

2. Discuss the two compartment open model Intra Venous administration.

3. Define Bioavailability. Explain various methods used for determination of
Bioavailability.

4. Explain the various models of Pharmacokinetic analysis.

II. Write notes on: (6 x 5 = 30)

1. What are the objectives and approaches in developing in vitro-in vivo correlation?
2. Causes of non-linearity with example.
3. Limitations of multi compartmental analysis.
4. Discuss the importance of salivary excretion of drugs.
5. Discuss in detail regulatory requirements for bioavailability study.
6. What are the factors affecting drug dissolution?


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