[LI 827] APRIL 2016 Sub. Code: 3827
PHARM. ‘D’ AND PHARM. ‘D’ (POST BACCALAUREATE) DEGREE EXAMINATION
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(2009-2010 Regulation)
FIFTH YEAR
PAPER III - CLINICAL PHARMACOKINETICS & PHARMACOTHERAPEUTIC DRUG MONITORING
Q.P. Code: 383827
Time : Three hours Maximum : 70 marks
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- I. Elaborate on : (4 x 10 =40)
- How will you determine the renal impairment in patients and discuss the extracorporeal removal of drugs?
- Explain the drug dosing in elderly and pediatrics patient.
- Discuss the adaptive methods with feedback in population pharmacokinetic.
- Explain in detail the drug dosage regimen for individual dosage.
- II. Write notes on : (6x5=30)
- Dosing of drug in hepatic disease: Effect of hepatic disease on pharmacokinetics.
- What is TDM and its protocol?
- Pharmacogenetics and Pharmacokinetics.
- Write about the conversion of intravenous to oral dosing.
- Pharmacokinetics drug interaction.
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