Sub. Code: 3827
PHARM. ‘D’ AND PHARM. ‘D’ (POST BACCALAUREATE) DEGREE EXAMINATION
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(2009-2010 Regulation)
FIFTH YEAR
PAPER III - CLINICAL PHARMACOKINETICS & PHARMACOTHERAPEUTIC DRUG MONITORING
Q.P. Code : 383827
Time : Three hours Maximum : 70 Marks
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- Elaborate on: (4 x 10 =40)
- Bayesian theory and its applications in population pharmacokinetics.
- Discuss pharmacokinetic drug interactions with examples.
- Dose adjustment in renal disease.
- TDM of drugs related to cardiovascular, seizure, psychiatric and organ transplantations.
- Write notes on: (6x5=30)
- Application of clinical pharmacokinetics.
- Dosing in obese patients.
- PK/PD correlation in drug therapy.
- P-Glycoprotein and Multidrug resistance.
- Genetic polymorphism in drug metabolism.
- Regional Pharmacokinetics.
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