Download Pharm D 5th Year 2017 May 383827 Clinical Pharmacokinetics And Pharmacotherapeutic Drug Monitoring Question Paper

Download Pharm-D (Doctor of Pharmacy) 5th Year (Fifth Year) 2017 May 383827 Clinical Pharmacokinetics And Pharmacotherapeutic Drug Monitoring Previous Question Paper

[LK 827] MAY 2017 Sub. Code: 3827

PHARM. ?D? AND PHARM. ?D? (POST BACCALAUREATE)
EGREE EXAMINATION
(2009-2010 Regulation)
FIFTH YEAR
PAPER III ? CLINICAL PHARMACOKINETICS &
PHARMACOTHERAPEUTIC DRUG MONITORING

Q.P. Code : 383827
Time : Three hours Maximum : 70 Marks

I. Elaborate on: (4 x 10 = 40)

1. Bayesian theory and its applications in population pharmacokinetics.

2. Discuss pharmacokinetic drug interactions with examples.

3. Dose adjustment in renal disease.

4. TDM of drugs related to cardiovascular, seizure, psychiatric and organ
transplantations.

II. Write notes on: (6 x 5 = 30)

1. Application of clinical pharmacokinetics.
2. Dosing in obese patients.
3. PK/PD correlation in drug therapy.
4. P-Glycoprotein and Multidrug resistance.
5. Genetic polymorphism in drug metabolism.
6. Regional Pharmacokinetics.
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