Download Pharm D 5th Year 2018 Oct 383827 Clinical Pharmacokinetics And Pharmacotherapeutic Drug Monitoring Question Paper

Download Pharm-D (Doctor of Pharmacy) 5th Year (Fifth Year) 2018 Oct 383827 Clinical Pharmacokinetics And Pharmacotherapeutic Drug Monitoring Previous Question Paper

[LN 827] OCTOBER 2018 Sub. Code: 3827

PHARM. ?D? AND PHARM. ?D? (POST BACCALAUREATE)
EGREE EXAMINATION
(2009-2010 Regulation)
FIFTH YEAR
PAPER III ? CLINICAL PHARMACOKINETICS &
PHARMACOTHERAPEUTIC DRUG MONITORING

Q.P. Code : 383827
Time : Three hours Maximum : 70 Marks

I. Elaborate on: (4 x 10 = 40)

1. Explain pharmacokinetic drug interactions with examples.

2. Genetic polymorphism in cytochrome P450 ISO enzymes.

3. Pharmacokinetic changes and dose adjustment in Hepatic disease.

4. Dose adjustment for renal failure and uremic patients.

II. Write notes on: (6 x 5 = 30)

1. Importance of Beysian theory.
2. Write brief note on personalized medicine or theraphy.
3. Drug dosing in paediatrics.
4. Nonlinear mixed effect model.
5. TDM of seizure drugs.
6. Dosing in obese patients.
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