PTU (Punjab Technical University) B.Pharmacy Second Semester May 2019 74969 BIOCHEMISTRY Question Paper
Total No. of Pages : 03
Total No. of Questions : 13
B.Pharma (2017 & Onwards) (Sem.-2)
BIOCHEMISTRY
Subject Code : BP-203T
M.Code : 74969
Time : 3 Hrs. Max. Marks : 75
INSTRUCTIONS TO CANDIDATES :
1.
SECTION-A is COMPULSORY consisting of TEN questions carrying T WO marks
each.
2.
SECTION-B contains T HREE questions carrying T EN marks each and student
has to attempt any T WO questions.
3.
SECTION-C contains NINE questions carrying FIVE marks each and student has
to attempt any SEVEN questions.
SECTION-A
Q1.
Answer briefly :
a) Amino acid residues present in protein are.......... amino acids.
i.
ii.
iii.
iv.
b) Formation of cyclic structure of glucose from open chain structure is an example
of..........
i. Nucleophilic addition
ii. Formation of hemi-acetal
iii. Formation of acetal
iv. i and ii
c) Sphingomylein is a derivative of .
i. Sphingosine
ii. Ceramide
iii. Phosphotidic acid
iv. i and ii.
d) For C-C bond in backbone of protein, the bond angle resulting from rotation at C is
labeled as
i.
ii.
iii.
iv. i and ii both
1 M-74969
(S29)-220
e) The successive nucleotides in DNA are linked through ............ bridge.
i. Phosphodiester
ii. Amide
iii. Glycosidic
iv. None of these
f) transports free fatty acid from cytosol to mitochondria.
i. Carnitine shuttle
ii. Citrate shuttle
iii. Both i and ii
iv. Neither i nor ii
g) ATP is
.
i. Nucleotide
ii. Energy link between anabolism and catabolism
iii. Hydrolysed with positive G
iv. All of the above
h) ...............is an essential amino acid.
i. Lysine
ii. Tyrosine
iii. Glycine
iv. Alanine.
i) Transfer of amino acid to a keto acid is known as
i. Transamination
ii. Deamination
iii. Transdeamination
iv. i and iii both.
j) Myocardial infarction can be diagnosed by isoenzyme of
i. LDH
ii. ALP
iii. SGOT
iv. ACP
2 M-74969
(S29)-220
SECTION-B
Q2
Give outline for gluconeogenesis. Explain its biochemical significance.
Q3
Describe the de novo synthesis of pyrimidine nucleotides. Comment on hyperuricemia.
Q4
Give IUB system of enzyme classification. Discuss the two diagnostic applications of
isoenzymes citing suitable examples.
SECTION-C
Q5
Explain various types of stereoisomerism present in monosaccharides.
Q6
Explain the mechanism of oxidative phosphorylation.
Q7
Describe the various steps involved in -oxidation.
Q8
Describe biosynthesis of catecholamines from tyrosine catabolism.
Q9
Discuss the biochemical causes of jaundice.
Q10
Describe reactions of Kreb-Henseleit cycle.
Q11
Describe post transcriptional modifications in primary transcripts of mRNA.
Q12
Give outline for the conversion of cholesterol to adrenal cortex hormone.
Q13
Give structure and biochemical significance of co-enzymes derived from Vitamin B2.
NOTE : Disclosure of Identity by writing Mobile No. or Making of passing request on any
page of Answer Sheet will lead to UMC against the Student.
3 M-74969
(S29)-220
This post was last modified on 05 November 2019