PTU (Punjab Technical University) B.Pharmacy Fourth Semester May 2019 75844 MEDICINAL CHEMISTRY I Question Paper
Total No. of Pages : 02
Total No. of Questions : 13
B.Pharma (2017 Batch) (Sem.-4)
MEDICINAL CHEMISTRY-I
Subject Code : BP-402T
M.Code : 75844
Time : 3 Hrs. Max. Marks : 75
INSTRUCTIONS TO CANDIDATES :
1.
SECTION-A is COMPULSORY consisting of TEN questions carrying T WO marks
each.
2.
SECTION-B contains T HREE questions carrying T EN marks each and student
has to attempt any T WO questions.
3.
SECTION-C contains NINE questions carrying FIVE marks each and student has
to attempt any SEVEN questions.
SECTION-A
1.
Explain the Terms :
a. Hydrogen bonding.
b. Optical activity.
c. Structure and IUPAC name of Phenytoin.
d. Chemical structure and therapeutic class of Phenobarbital.
e. Differentiate between general and partial seizures.
f. Types of autonomic nervous system.
g. What do you mean by ultra short acting barbiturates, name two?
h. Name and give structure of Adrenergic neurotransmitters.
i. Bioisosterisism.
j. Synthesis of Neostigmine .
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SECTION-B
2.
Give detailed account of anti-inflammatory agents.
3.
Synthesis and mechanism of action of two anti-convulsants.
4.
Name the neurotransmitters responsible for psychosis. Give the symptoms and discuss
any drugs used for its treatment in details.
SECTION-C
5.
Short note on Inhalation anaesthtetics.
6.
Synthesis and mechanism of action of Carbacol.
7.
Phase II metabolism.
8.
Biosynthesis and metabolite of dopamine.
9.
Structure activity relationship of Cholinolytic agnets.
10. Alpha adrenergic blockers.
11. Factors affecting metabolism.
12. Biosynthesis and physiological role of GABA.
13. Structure and chemical name of morphine and its two related analogues.
NOTE : Disclosure of Identity by writing Mobile No. or Making of passing request on any
page of Answer Sheet will lead to UMC against the Student.
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This post was last modified on 05 November 2019