PTU B-Pharma 7th Semester May 2019 71756 PHARMACEUTICAL CHEMISTRY VII Question Paper

Roll No.

Total No. of Questions : 10

Total No. of Pages : 02

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B.Pharma (2011 to 2016) (Sem.-7)

PHARMACEUTICAL CHEMISTRY-VII

(Medicinal Chemistry-II)

Subject Code : BPHM-704

M.Code: 71756

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Time: 3 Hrs.

Max. Marks : 80

INSTRUCTIONS TO CANDIDATES :

1. SECTION-A is COMPULSORY consisting of FIFTEEN questions carrying TWO marks each.
2. SECTION-B contains FIVE questions carrying FIVE marks each and students have to attempt any FOUR questions.

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3. SECTION-C contains FOUR questions carrying TEN marks each and students have to attempt any THREE questions.

SECTION-A

1. Answer briefly :
1. Give chemical structure and uses of cholesterol.
2. What are anabolic agents?

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3. Name two intravenous anesthetics.
4. Write synthesis of pentazocine.
5. What are centrally acting antitussives?
6. Write chemical structure and uses of nikethamide.
7. Write chemical structure and uses of acetozolamide.

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8. What are butyrophenones?
9. Which alkaloid has antiarrhythmic activity?
10. What are atypical antidepressants?
11. Write chemical structure and uses of propranolol.
12. Discuss the role of vitamin K as anticoagulant.

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13. What is methyldopa?
14. Define Antihyperlipidemics with examples.
15. Define Opioid antagonists with example.

SECTION-B

2. Write in detail about synthesis, mode of action and medicinal uses of diazepam.

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3. Describe synthetic procedure for oestradiol and stilboestrol.
4. How can you classify local anesthetics? Give chemical synthesis of lignocaine.
5. Give the synthesis, mode of action of phenytoin and frusemide.
6. Discuss structure activity relationship of phenothiazine class of antipsychotics.

SECTION-C

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7. What are Androgens? Explain biosynthesis of testosterone and its synthesis from diosgenin.
8. Give an account of cardiac glycosides and their role in the treatment of heart failure.
9. Discuss medicinal chemistry of halogenated hydrocarbons used as general anesthetics.
10. Write an account of barbiturates as sedative and hypnotics. Give synthesis of phenobarbitone.

NOTE : Disclosure of Identity by writing Mobile No. or Making of passing request on any page of Answer Sheet will lead to UMC against the Student.

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