PTU (Punjab Technical University) B.Pharmacy Seventh Semester May 2019 Question Paper
Total No. of Pages : 02
Total No. of Questions : 10
B.Pharma (2011 to 2016) (Sem.?7)
PHARMACEUTICAL CHEMISTRY?VII
(Medicinal Chemistry-II)
Subject Code : BPHM-704
M.Code : 71756
Time : 3 Hrs. Max. Marks : 80
INSTRUCTIONS TO CANDIDATES :
1.
SECTION-A is COMPULSORY consisting of FIFTEEN questions carrying T WO
marks each.
2.
SECTION-B contains FIVE questions carrying FIVE marks each and students
have to attempt any FOUR questions.
3.
SECTION-C contains FOUR questions carrying T EN marks each and students
have to attempt any T HREE questions.
SECTION-A
1.
Answer briefly :
(a) Give chemical structure and uses of cholesterol.
(b) What are anabolic agents?
(c) Name two intravenous anesthetics.
(d) Write synthesis of pentazocine.
(e) What are centrally acting antitussive?
(f) Write chemical structure and uses of nikethamide.
(g) Write chemical structure and uses of acetozolamide.
(h) What are butyrophenones?
(i) Which alkaloid has antiarrrythmic activity?
(j) What are atypical antidepressants?
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(k) Write chemical structure and uses of propranolol.
(1) Discuss the role of vitamin K as anticoagulant.
(m) What is methyldopa?
(n) Define Antihyperlipidemics with examples.
(o) Define Opioid antagonists with example.
SECTION-B
2.
Write in detail about synthesis, mode of action and medicinal uses of diazepam.
3.
Describe synthetic procedure for oestradiol and stilboestrol.
4.
How can you classify local anasesthetics? Give chemical synthesis of lignocaine.
5.
Give the synthesis, mode of action of phenytoin and frusemide.
6.
Discuss structure activity relationship of phenothiazine class of antipsychotics.
SECTION-C
7.
What are Androgens? Explain biosynthesis of testosterone and its synthesis from
diosgenin.
8.
Give an account of cardiac glycosides and their role in the treatment of heart failure.
9.
Discuss medicinal chemistry of halogenated hydrocarbons used as general anesthetics.
10. Write an account of barbiturates as sedative and hypnotics. Give synthesis of
phenobarbitone.
NOTE : Disclosure of Identity by writing Mobile No. or Making of passing request on any
page of Answer Sheet will lead to UMC against the Student.
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This post was last modified on 05 November 2019