Q.P.CODE:152-NR
Dr. NTR University of Health Sciences: Vijayawada-520 008
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M.D. DEGREE EXAMINATION — MAY, 2017
PHARMACOLOGY
Paper-I : Pharmacology General Principles and Experimental Pharmacology including Biostatistics and Bio-assay.
Time: 3 Hours Max. Marks:100
Note: Answer all questions
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All questions carry equal marks
Draw neat diagrams wherever necessary
- WRITE SHORT ESSAYS ON THE FOLLOWING:
- Mention the various routes of drug administration and their advantages, with examples. Add a brief note on liposome based drug delivery.
- Describe the various pathological states which effect drug action, giving examples.
- Describe the phases of clinical drug trials. Describe the features of an ideal Randomized Clinical trial
- Describe briefly the statistical tests used to compare means and proportions
- Write a brief note on teratogenicity and carcinogenicity of drugs. Briefly describe how drugs are tested for theses effects.
- HPLC (High Performance Liquid Chromatography) and its applications
- Animal use in drug testing
- Define the pharmacokinetic and pharmacodynamic types of drug interactions. Add a brief note on drug interactions with warfarin.
- Define drug bioavailability. Mention the factors which affect drug bioavailability
- Pharmacovigilance
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