UNIVERSITY OF JAFFNA
BACHELOR OF PHARMACY
FIRST YEAR SECOND SEMESTER EXAMINATION - JULY 2015
PHACE 1284 PHARMACEUTICS I — PAPER If
Date: 15.07.2015.
Time: 02 Hours
ANSWER ALL EIGHT QUESTIONS.
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1.1 List the types of tablets. (20 Marks)
1.2 List the advantages and disadvantages of tablets. (30 Marks)
1.3 Explain the manufacturing defects of tablets. (50 Marks)
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2.2 List the properties of suspension. (40 Marks)
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2.3 List the pharmaceutical applications of suspensions. (30 Marks)
2.4 List the pharmaceutical uses of emulsion. (30 Marks)
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3.1 Explain why some drugs are not suitable for oral route? (30 Marks)
3.2 List the ideal properties of suppository bases. (30 Marks)
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3.3 List the advantages of synthetic tri-glycerides over cocoa butter. (40 Marks)
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4.1 List the ideal properties of ointment bases. (30 Marks)
4.2 Briefly describe the various types of ointment bases. (50 Marks)
4.3 Differentiate the ointment and cream. (20 Marks)
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5.1 Describe the importance of extracts. (30 Marks)
5.2 Explain the qualities of ideal allergenic extracts. (20 Marks)
5.3 List the errors that could occur during measurement of liquids. (50 Marks)
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6.1 Classify bulk powders. (20 Marks)
6.2 Describe the each types of bulk powder mentioned in 6.1 (40 Marks)
6.3 Define the following.
- 6.3.1 Aromatic water (10 Marks)
- 6.3.2 Elixir (10 Marks)
- 6.3.3 Radiopharmaceuticals (10 Marks)
- 6.3.4 Liniments (10 Marks)
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7.1 List the medicinal gases. (10 Marks)
7.2 How will you identify cylinders containing medicinal gases. (40 Marks)
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7.3 Briefly describe the safe handling of medicinal gas cylinders. (50 Marks)
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8.1 List the excipients used in the soft gelatine capsules. (20 Marks)
8.2 Calculate the amount of 2% of ointment that must be added to 30 gram of 15% ointment to prepare 5% ointment? (40 Marks)
8.3 Calculate the amount of base for the preparation of bismuth subgallate suppositories each containing 300 mg of drug and weighing 1 gram (displacement value of bismuth subgallate is 3). (40 Marks)
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