Download University of Jaffna, Sri Lanka B.Pharma 2nd Year 2015 July 2202 Pharmaceutics III Question Paper

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UNIVERSITY OF JAFFNA
BACHELOR OF PHARMACY
SECOND YEAR SECOND SEMESTER EXAMINATION - JULY 2015
PHACE 2202 PHARMACEUTICS III - PAPER II
Date: 15.07.2015. Time:
ANSWER ALL EIGHT QUESTIONS
02 Hours
1.
1.1 Briefly explain how colloidal particles acquire charges. (50 Marks)
1.2 Describe the electrical double layer of colloidal particles. (50 Marks)
2.
2.1 What is coarse dispersion? (10 Marks)
2.2 Differentiate flocculated and deflocculated suspensions. (30 Marks)
2.3 Describe
2.3.1 the factors causing instability of emulsion. (30 Marks)
2.3.2 how the above instabilities of emulsion can be prevented. (30 Marks)
3.
3.1 List the factors that affect the dissolution rate of solids (20 Marks)
3.2 Solubility of weak electrolytes is more in the optimum pH.
Explain with suitable derivation (50 Marks)
3.3 Describe the dissolution of solid based on the Noyes Whitney's
Equation (30 Marks)
4.
4.1 What is thixotropy? (10 Marks)
4.2 Describe the mechanism of thixotropy (30 Marks)
4.3 Explain the applications of rheology in pharmacy (60 Marks)
5.
5.1 What is surfactant? (10 Marks)
5.2 Classify surfactants with examples (20 Marks)
5.3 Explain the applications of following in pharmacy
5.2.1 surfactants (30 Marks)
5.2.2 adsorption (40 Marks)
6.
6.1 List the factors responsible for the cohesion of powders? (30 Marks)
6.2 Describe how cohesion can be quantified? (35 Marks)
6.3 Explain how flow properties of powder can be improved? (35 Marks)
7. 7.1 Based on the Arrhenius equation how shelf life of
pharmaceuticals could be determined.
(50 Marks)
7.2 Briefly explain the theories of catalysis. (30 Marks)
7.3 What is the significance of photochemistry in pharmacy (20 Marks)
Page 1 of 2
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UNIVERSITY OF JAFFNA
BACHELOR OF PHARMACY
SECOND YEAR SECOND SEMESTER EXAMINATION - JULY 2015
PHACE 2202 PHARMACEUTICS III - PAPER II
Date: 15.07.2015. Time:
ANSWER ALL EIGHT QUESTIONS
02 Hours
1.
1.1 Briefly explain how colloidal particles acquire charges. (50 Marks)
1.2 Describe the electrical double layer of colloidal particles. (50 Marks)
2.
2.1 What is coarse dispersion? (10 Marks)
2.2 Differentiate flocculated and deflocculated suspensions. (30 Marks)
2.3 Describe
2.3.1 the factors causing instability of emulsion. (30 Marks)
2.3.2 how the above instabilities of emulsion can be prevented. (30 Marks)
3.
3.1 List the factors that affect the dissolution rate of solids (20 Marks)
3.2 Solubility of weak electrolytes is more in the optimum pH.
Explain with suitable derivation (50 Marks)
3.3 Describe the dissolution of solid based on the Noyes Whitney's
Equation (30 Marks)
4.
4.1 What is thixotropy? (10 Marks)
4.2 Describe the mechanism of thixotropy (30 Marks)
4.3 Explain the applications of rheology in pharmacy (60 Marks)
5.
5.1 What is surfactant? (10 Marks)
5.2 Classify surfactants with examples (20 Marks)
5.3 Explain the applications of following in pharmacy
5.2.1 surfactants (30 Marks)
5.2.2 adsorption (40 Marks)
6.
6.1 List the factors responsible for the cohesion of powders? (30 Marks)
6.2 Describe how cohesion can be quantified? (35 Marks)
6.3 Explain how flow properties of powder can be improved? (35 Marks)
7. 7.1 Based on the Arrhenius equation how shelf life of
pharmaceuticals could be determined.
(50 Marks)
7.2 Briefly explain the theories of catalysis. (30 Marks)
7.3 What is the significance of photochemistry in pharmacy (20 Marks)
Page 1 of 2
8.1 What is inclusion complex? (10 Marks)
8.2 List the different types of inclusion complexes. (20 Marks)
8.3 List the various methods used for the analysis of complexes. (20 Marks)
8.4 Write a note on cyclodextrin. (50 Marks)
8.
Page 2 of 2
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