UNIVERSITY OF JAFFNA
BACHELOR OF PHARMACY
SECOND YEAR SECOND SEMESTER EXAMINATION - JULY 2015
PHACE 2202 PHARMACEUTICS III - PAPER II
Date: 15.07.2015.
Time: 02 Hours
ANSWER ALL EIGHT QUESTIONS
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- Briefly explain how colloidal particles acquire charges. (50 Marks)
- Describe the electrical double layer of colloidal particles. (50 Marks)
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- What is coarse dispersion? (10 Marks)
- Differentiate flocculated and deflocculated suspensions. (30 Marks)
- Describe
- the factors causing instability of emulsion. (30 Marks)
- how the above instabilities of emulsion can be prevented. (30 Marks)
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- List the factors that affect the dissolution rate of solids (20 Marks)
- Solubility of weak electrolytes is more in the optimum pH. Explain with suitable derivation (50 Marks)
- Describe the dissolution of solid based on the Noyes Whitney's Equation (30 Marks)
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- What is thixotropy? (10 Marks)
- Describe the mechanism of thixotropy. (30 Marks)
- Explain the applications of rheology in pharmacy (60 Marks)
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- What is surfactant? (10 Marks)
- Classify surfactants with examples (20 Marks)
- Explain the applications of following in pharmacy
- surfactants (30 Marks)
- adsorption (40 Marks)
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- List the factors responsible for the cohesion of powders? (30 Marks)
- Describe how cohesion can be quantified? (35 Marks)
- Explain how flow properties of powder can be improved? (35 Marks)
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- Based on the Arrhenius equation how shelf life of pharmaceuticals could be determined. (50 Marks)
- Briefly explain the theories of catalysis. (30 Marks)
- What is the significance of photochemistry in pharmacy (20 Marks)
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- What is inclusion complex? (10 Marks)
- List the different types of inclusion complexes. (20 Marks)
- List the various methods used for the analysis of complexes. (20 Marks)
- Write a note on cyclodextrin. (50 Marks)
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