Download University of Jaffna, Sri Lanka B.Pharma 2nd Year 2015 July 2203 Pharmacology Question Paper

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UNIVERSITY OF JAFFNA, SRI LANKA

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BACHELOR OF PHARMACY

SECOND YEAR SECOND SEMESTER EXAMINATION JULY 2015

PHACL 2203 - PHARMACOLOGY & PHARMACOTHERAPY II

Date: 11.07.2015

Paper II

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Time: 02 hours

ANSWER ALL FOUR QUESTIONS

1. 1. Name five anticholinesterases. (20 Marks)
   2. List the indications of anticholinesterases with examples. (30 marks)
   3. Explain the clinical manifestations of organophosphate poisoning. (50 Marks)

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2. 1. Describe the mechanism of actions for warfarin. (10 Marks)
   2. List the indications of warfarin. (20 Marks)
   3. Explain the drug interactions of warfarin with examples. (40 Marks)
   4. Write the advice that you would give to the patient when dispensing warfarin. (30 Marks)

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3. 1. Describe the mechanism of action of methotrexate in
      1. rheumatoid arthritis. (10 Marks)
      2. cancer chemotherapy. (10 Marks)
   2. Explain the adverse effects of methotrexate at the dosage used for the treatment of rheumatoid arthritis. (40 Marks)

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   3. Write the precautions that need to be taken to prevent the adverse effects mentioned in 3.2. (20 Marks)
4. Write an account on
   1. cardio-selective beta blockers. (30 Marks)
   2. oral iron therapy. (30 Marks)
   3. inhaled steroids in bronchial asthma. (40 Marks)

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