Download University of Jaffna, Sri Lanka B.Pharma 3rd Year 2015 July 3201 Pharmacology Question Paper

UNIVERSITY OF JAFFNA, SRI LANKA

BACHELOR OF PHARMACY

THIRD YEAR SECOND SEMESTER EXAMINATION— JULY 2015

--- Content provided by⁠ FirstRanker.com ---

PHARMACOLOGY & PHARMACOTHERAPY IV PHACL 3201

Date: 14.07.2015

Paper II

Time: 02 hours

ANSWER ALL THE FOUR QUESTIONS

--- Content provided by‌ FirstRanker.com ---

1. 1. Describe the mechanism of action of benzodiazepines. (10 Marks)
   2. Describe the differences in the pharmacokinetic properties among the different types of benzodiazepines. (20 Marks)
   3. List the indications of benzodiazepines with examples. (30 Marks)
   4. What are the adverse effects of benzodiazepines. (20 Marks)
   5. List the differences between benzodiazepines and non-benzodiazepine hypnotics (20 Marks)

   --- Content provided by‌ FirstRanker.com ---

2. Explain the pharmacological basis for
   1. giving folic acid supplementation with phenytoin. (20 Marks)
   2. combining levodopa and carbidopa. (20 Marks)
   3. adding adrenaline to local anaesthetic agents. (20 Marks)
   4. using antimuscarinic agents in the treatment of drug-induced parkinsonism. (20 Marks)

   --- Content provided by​ FirstRanker.com ---

   5. using triptans in the treatment of migraine. (20 Marks)
3. 1. Give one example for
      1. depolarizing neuromuscular blockers. (05 Marks)
      2. non-depolarizing neuromuscular blockers. (05 Marks)

   --- Content provided by‍ FirstRanker.com ---

   2. Describe the mechanism of action of
      1. depolarizing neuromuscular blockers. (10 Marks)
      2. non-depolarizing neuromuscular blockers. (10 Marks)
   3. List the indications for neuromuscular blockers. (10 Marks)
   4. What are the adverse effects of neuromuscular blocker? (20 Marks)

   --- Content provided by‌ FirstRanker.com ---

   5. Explain the pharmacokinetics of inhaled anesthetic agents. (40 Marks)
4. Write an account on
   1. pharmacovigilance. (30 Marks)
   2. pharmacokinetic and pharmacodynamic changes in elderly. (30 Marks)
   3. opioid analgesics. (40 Marks)

   --- Content provided by‍ FirstRanker.com ---

Page 1 of 1

FirstRanker.com