Download University of Jaffna, Sri Lanka B.Pharma 4th Year 2016 January 4104 Natural Product Chemistry Jan Question Paper

Download University of Jaffna, Sri Lanka (University of Sri Lanka,) B.Pharma (Bachelor of Pharmacy) Fourth Year (4th Year) 2016 January 4104 Natural Product Chemistry Jan Last 10 Years 2020, 2019, 2018, 2017, 2016, 2015, 2014, 2013, 2012, 2011 and 2010 Previous Question Papers.

UNIVERSITY OF JAFFNA, SRI LANKA
BACHELOR OF PHARMACY
FOURTH YEAR FIRST SEMESTER EXAMINATION ? JANUARY 2016
PHANP 4104 NATURAL PRODUCT CHEMISTRY - PAPER II
Date: 27.01.2016 Time: 2 Hours
Answer all Six questions.
Classify the naturally occurring purines.
How can you confirm the position of oxygen atom at C6 position in caffeine?
Indicate how theophylline could be synthesized from uric acid?
(20 Marks)
(40 Marks)
(40 Marks)
2. 2.1 List the active compounds in adrenal cortex extract.
2.2 Draw the chemical structures for the following compounds.
2.2.1 Prednisolone
2.2.2 Beclomethasone
2.2.3 Hydrocortisone
2.3 Show how do you synthesize testosterone by microbiological method?
3. 3.1 Give the basic structure of betalactum antibiotics.
3.2 Draw the structures of five naturally occurring Penicillins.
3.3 Discuss the Structure Activity Relationship of Penicillins.
4 4.1 Name the sugars and their linkage present in Streptomycin.
4.2 How will you detect the presence of nitro group in chloramphenicol?
4.3 Give the synthesis of Chloramphenicol starting from p-nitroacetophenone.
5 Write short notes on
5.1 Diel' s hydrocarbon.
5.2 Murexide reaction of uric acid.
5.3 Natural Oestrogens.
6 6.1 List the natural bile acids.
6.2 How can you isolate bile acid from natural bile?
6.3 Draw the synthesis of progesterone from a sapogenin glycoside.
(30 Marks)
(30 Marks)
(40 Marks)
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(40Marks)
(40 Marks)
(15 Marks)
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(65 Marks)
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