M.B.B.S. DEGREE EXAMINATION – JANUARY, 2013
SECOND M.B.B.S. EXAMINATION
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PATHOLOGY
(GENERAL PATHOLOGY & HAEMATOLOGY)
PAPER-I
507-A
Time: 2 Hours Max.
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Marks: 40
Answer all questions
- An young and stout male met with an accident. He sustained multiple injuries, fractures of femur and tibia. These fractures are stabilized at Surgery soon after admission. He is in a stable condition. However 2 days after admission he suddenly becomes dyspneic and developed tachypnea and tachycardia, irritability, restlessness and it progressed to delirium, coma and death on 7th day.
- What is the provisional diagnosis?
- Discuss the pathogenesis of the lesion
- Describe microscopic picture of the Lungs in the above condition.
- How "Frozen sections" of the lung tissue help in final diagnosis at autopsy and mention various stains specific for it? 1+4+2+3 = 10
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WRITE SHORT NOTES ON: 5x4=20
- Protein derived mediators of acute inflammation.
- Down Syndrome
- Pathogenesis of Amyloidosis
- Physical carcinogenesis
- Blood and Bone marrow findings in Aplastic anemia.
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WRITE BRIEFLY ON: 5x2=10
- Mention 4 sequelae of Ghon's complex
- Name 4 main components of Extra cellular Matrix (ECM)
- Name 4 morphologic changes (cytoplasmic & Nuclear) in necrotic cell.
- Name 4 Blood components separated from whole blood and mention one clinical use for each.
- Mention 4 morphologic characteristics of a Myeloblast.
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