507-A
M.B.B.S. DEGREE EXAMINATION – JANUARY, 2014
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SECOND M.B.B.S. EXAMINATION
PATHOLOGY
(GENERAL PATHOLOGY & HAEMATOLOGY)
PAPER-I
Time : 2 Hours | Max. Marks: 40 |
Answer all questions
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- A male child aged 8 years presented with fever, fatigue, generalized lymphadenopathy, bone pain, petechial hemorrhages over the skin, pallor, enlarged testes and features of meningism.
- What is the provisional diagnosis?
- Describe blood and bone marrow picture and
- Other investigations to confirm the diagnosis.
- Discuss the prognosis of the same. (1+4+3+2=10)
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WRITE SHORT NOTES ON: 5x4=20
- Etiology and pathogenesis of fat embolism
- Mention Arachidonic acid metabolites and their role in inflammation.
- Tabulate the differentiating features of Necrosis and Apoptosis
- Describe the chemical nature of Amyloid
- Describe the steps / events involved in mechanism of tumor INVASION and METASTASIS
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WRITE BRIEFLY ON: 5x2=10
- Name any four (4) pathological changes in Vitamin A deficiency
- Name any four (4) growth factors involved in regeneration and wound healing
- Name one (1) infectious disease and three (3) tumors caused by Epstein-Barr virus
- Name three (3) X-linked recessive and one (1) X-linked dominant disorders
- Name two (2) special stains for reticulocytes and two (2) causes of Reticulocytosis.
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