Download SGBAU BSc 2019 Summer 5th Sem Bioinformatics Methods In Bioinformatics Question Paper

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Time: Three Hours] [Maximum Marks : 80

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B.Sc. (Part-III) Semester—V Examination

5S : BIOINFORMATICS

(Methods in Bioinformatics)

Note :— (1) All questions are compulsory.
(2) Draw well labelled diagram wherever necessary.

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1. (a) Fill in the blanks :
   1. __________ is an information retrieval system of NCBI.
   2. __________ is a protein information resource database.
   3. The FASTA format of sequence begins with __________ symbol.
   4. GenBank is maintained by __________.

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2. (b) Choose the correct alternative :
   1. All are nucleotide sequences databases except :
      (a) Swiss-Prot (b) EMBL
      (c) DDBJ (d) GenBank
   2. Phylogenetic relationship can be shown by :
      (a) Dendrogram (b) GenBank
      

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      (c) Data tool (d) Tendrogram
   3. BLAST program is used for :
      (a) DNA sequencing (b) Sequence alignment
      (c) Basic sequence searching (d) DNA barcoding
   4. Which of the following is protein tertiary structure prediction method ?
      

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      (a) BLAST (b) SRS
      (c) Homology modeling (d) HMM
3. (c) Answer in one sentence each :
   1. What is EST ?
   2. What is RDBMS ?

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   3. What is genome ?
   4. What is sequence alignment ?

1. (a) What is database ? Types of databases.
2. (b) Describe the enzyme database.

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3. (c) Describe Data management and Architecture.

OR

1. (d) What is data security ?
2. (e) Explain database design.

1. (a) Explain GenBank as a database.

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2. (b) What are the limitations of computer analysis ?
3. (c) Describe transcription.

OR

1. (d) Describe structural organizations of genome.
2. (e) Describe STS.

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1. (a) Describe Genome databases.
2. (b) Explain BLAST tool and its types.

OR

1. (c) Explain protein translation and genetic code.
2. (d) Describe protein sequence database.

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1. (a) Describe protein structure database.
2. (b) Describe GenBank file format.

OR

1. (c) Describe restriction maps.
2. (d) Explain SRS features.

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1. (a) Describe GenBank libraries.
2. (b) Explain structural level of proteins.

OR

1. (c) Explain protein tertiary structure prediction methods.
2. (d) Explain HMM application in sequence alignment.

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1. (a) Explain features of Bioperl.
2. (b) What is sequence Homology ?

OR

1. (c) Write applications of HMM in structure prediction.
2. (d) Describe parsing of BLAST output.

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3. (e) Describe BLAST string matching in Bioperl.