Download NTRUHS MD/ MS PG 2013 April Question Papers Paper IV 151 NR Biochemistry

Download NTRUHS (Dr. NTR University of Health Sciences) MD/MS (Doctor of Medicine/ Master of Surgery) PG 2013 April Paper IV 151 NR Biochemistry Previous Question Papers

151-NR
M.D. DEGREE EXAMINATION ? APRIL, 2013
BIOCHEMISTRY
Paper-IV : Clinical Biochemistry
Time: 3 Hours Max. Marks:100
Note: Answer all questions
All questions carry equal marks

WRITE SHORT ESSAYS ON THE FOLLOWING:

1. A 35 year old woman was admitted in the hospital with history of
recurrent pain in the abdomen, developed jaundice 2 days later. Past
history revealed that the pain often aggravated after in take of fatty food.
Routine urine examination showed the presence of bile pigments and bile
salts, but urobilinogen was absent.

a) What is the probable diagnosis?
b) Give reasons for the excretion of bile pigments and bile salts in
urine.
c) Justify which other biochemical tests should be done in this patient
to confirm the diagnosis.

2. Classify tumor markers. What is an ideal tumor marker? Discuss the role
of molecular markers for cancer diagnosis

3. A 55 year old man who is a known smoker developed worsening cough
with thick sputum and was admitted to hospital with difficulty in
breathing. He was drowsy and cyanosed. His arterial blood gas analysis
was as follows:
P
H
? 7.2, p
CO2
? 70mm H
g
, HCO3 ? 26 mmol/L, PO2 ? 50 mm H
g

a) What is the probable acid-base disturbance? Mention the probable
causes of the same
b) Explain how the primary defect can be compensated in the body.

4. Discuss the analytical errors commonly encountered in the Clinical
Biochemistry lab.

5. Write briefly on:
a) Homocystinuria
b) EQAS

6. Explain the various biochemical and calculated methods of determining
glomerular filtration rate.
Contd?2

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