Download JNTUK B.Pharm 2-1 2013 B2104 Advanced Pharmaceutical Organic Chemistry Question Paper

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R10

Code No: B2104/R10

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II B.Pharmacy I Semester Supplementary Examinations, Dec 2013

ADVANCED PHARMACEUTICAL ORGANIC CHEMISTRY

Time: 3 hours

Max Marks: 75

Answer any FIVE Questions

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All Questions carry equal marks

1. (a) Give the examples with structure for fused ring systems with one hetero atom and write a note on aromaticity of Indole
   (b) Write the reactions of Indole.
2. (a) Discuss the structure and reactions of Benzimidazole?
   (b) Discuss the structure and reactions of Phenothiazine?

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3. Explain the following
   a) Racemisation
   b) Chirality
   c) Sequence rules
   d) Asymmetric synthesis.

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4. (a) What are monosaccharides? Give classification of monosaccharides with suitable examples.
   (b) Write a note on pharmaceutical importance of carbohydrates.
5. Write briefly on:
   (a) Physical properties of Amino acids, polypeptides and proteins
   (b) Important reactions of Amino acids.
   

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   (c) Isoelectric point.
6. (a) What are glycosides? Classify them with examples?
   (b) Enzymatic hydrolysis and mutarotation
   (c) Characterization of lipids
   (d) Rancidity of oils and fats

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7. (a) Define the terms nucleic acids, nucleotides and nucleosides with examples
   (b) Write an account on structure of DNA & RNA
8. Write the detailed mechanism and applications of:
   (a) Beckmann rearrangement
   (b) Phillips condensation reaction
   

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   (c) Mannich reaction
   (d) Michael addition reaction

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