QP Code 106001
Reg. No.:................
First Professional MBBS Degree Supplementary Examinations, February 2013
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Time: 3 hrs
BIOCHEMISTRY - PAPER II
Max marks : 50
- Answer all questions
- Draw diagrams wherever necessary
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Essay (10)
- Describe how protein is synthesized in body. Name any two inhibitors of protein biosynthesis. Add a note on post translational modifications. (6+2+2=10)
Short essays (2x5=10)
- Outline the degradation of heme. Add a note on fate of conjugated bilirubin in intestine.
- Explain briefly on storage and absorption of iron from intestine.
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Short notes (5x3=15)
- Define gout. Mention the causes of primary gout.
- Explain the role of kidney in acid base regulation.
- List the restriction endonucleases and mention its uses.
- Mention the principle and application of polymerase chain reaction.
- Explain the structure of IgG molecule and indicate its function.
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Answer briefly (5x2=10)
- Name the coenzyme forms of niacin and write important functions for each one of them.
- Wilson's disease.
- What is metabolic acidosis. Mention one example of a disease associated with it.
- List two examples of detoxification by conjugation.
- What is post hepatic jaundice and how it is diagnosed biochemically.
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Give precise answers (5x1=5)
- Pro vitamin and mention one example.
- Clinical features of rickets.
- One example for point mutation.
- Enzymes commonly used in ELISA technique.
- Xeroderma pigmentosum is due to deficiency of.
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