Download KUHS MBBS 2nd Year 2013 April 201001 Pharmacology Paper I Question Paper

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Code: 201001 Reg. no.: ...............

Second Professional MBBS Degree Examinations, April 2013

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Pharmacology- Paper I

Time: 3 Hours Total Marks: 40

• Answer all questions
• Draw diagrams wherever necessary

Essays: (2x6=12)

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1. A 24-year-old man is brought to the hospital with complaints of unconsciousness, sustained contractions (tonic) of all the body muscles followed by periods of muscle contraction alternating with periods of relaxations (clonic) lasting 1 to 2 minutes. Answer the following:
   • What are the drugs that can be prescribed to this patient.
   • Describe the pharmacokinetics and adverse effects of any one such drug. (2+3+1=6)
   • What is the treatment of status epilepticus.
2. Classify diuretic agents. Describe the mechanism of action, uses and adverse effects of furosemide. (2+2+1+1=6)

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Short notes: (5x3=15)

3. Calcium channel blockers
4. Drug treatment of anti cholinesterase poisoning
5. Kinetics of elimination
6. Halothane

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7. Nicorandil

Answer briefly: (5x1=5)

8. Rationale of combining beta blockers with long acting nitrates
9. Clinical uses of prostaglandins
10. Mechanism of action of disulfiram

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11. Flumazenil
12. Hofmann elimination

Name two drugs for: (8x1=8)

13. Drugs used in Myasthenia gravis
14. Uterine relaxants

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15. Mast cell stabilizers
16. Mucolytics
17. Low molecular weight heparins
18. Anti platelet drugs
19. Drug induced parkinsonism

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20. 5HT antagonists

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