Download KUHS MBBS 2nd Year 2013 Sept 201001 Pharmacology Paper I Question Paper

Q.P. Code: 201001

Reg. no.: ........................

Second Professional MBBS Degree Supplementary Examinations, September 2013

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Pharmacology- Paper I

Time: 2 Hours

Total Marks: 40

• Answer all questions
• Draw diagrams wherever necessary

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Essays: (2x6=12)

1. Classify non-steroidal anti inflammatory drugs. List the uses of NSAIDs. Mention four differences between aspirin and celicoxib. (2+2+2=6)
2. A 50 year old man develops pedal edema and also has difficulty in breathing. Echocardiography confirms mild congestive cardiac failure. Answer the following:
   • What are the first line drugs in congestive cardiac failure.
   • What is the rationale for use of each of them in congestive cardiac failure
   • Mention the life style modification that you would advise to this patient

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   • Add a note on treatment of digoxin over dosage (1+2+1+2=6)

Short notes: (5x3=15)

3. Microsomal enzyme induction
4. Carbamazepine

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5. Nasal decongestants
6. Treatment of organophosphorus poisoning
7. Diazepam

Answer briefly: (5x1=5)

8. Mention two uses and two adverse effects of chlorpromazine

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9. Discuss the rationale for the use of adrenaline in anaphylactic shock
10. Mechanism of action of lignocaine
11. What is a pro drug and mention two examples
12. List two advantages of low molecular weight heparin over standard heparin

Name two drugs for: (8x1=8)

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13. Bronchodilators (of two different groups)
14. Non sedative antihistamines
15. Angina pectoris
16. Cardio selective beta blockers
17. Two intravenous and two inhalational anaesthetics

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18. Anti hypertensives used in emergencies
19. Peripherally acting skeletal muscle relaxants
20. Name the antidote in poisoning due to paracetamol and methanol

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