Download KUHS MBBS 2nd Year 2018 Feb 201001 Pharmacology Paper I Question Paper

Q.P. Code: 201001

Reg. no.: ........................

Second Professional MBBS Degree Examinations February 2018

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Pharmacology- Paper I

Time: 2 Hours

Total Marks: 40

• Answer all questions
• Draw diagrams wherever necessary

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Essays: (2x6=12)

1. Classify antihypertensive drugs. Describe the mechanism of action, uses and adverse effects of angiotensin converting enzyme (ACE) inhibitors. (2+2+1+1)
2. Sarala, 28 years old lady was suffering from depression. The physician prescribed tablet fluoxetine 20mg/day for her. Answer the following:
   • What is the mechanism of action of fluoxetine.
   • What is the advantage of this drug compared to tricyclic antidepressants.
   • What can happen if this patient is administered pethidine concurrently (2+2+2)

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Short notes: (5x3=15)

3. Plasma half life
4. Edrophonium
5. Sumatriptan

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6. Propofol
7. Clopidogrel

Answer briefly: (5x1=5)

8. Tachyphylaxis. Give examples
9. Why is benzhexol used in the treatment of drug induced Parkinsonism.

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10. Explain the use of propranolol in thyrotoxicosis.
11. Rationale of using low dose aspirin in post myocardial infarction.
12. Atracurium

Name two drugs: (8x1=8)

13. Available as transdermal patch

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14. Used in the treatment of atrial fibrillation
15. Potassium sparing diuretics
16. Used in treatment of acute congestive glaucoma
17. Histamine releasers
18. In treatment of absence seizures

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19. Fibrinolytic agents
20. Disease modifying anti-rheumatic drugs

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