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RoIINo.‘ ‘ ‘ ‘ ‘ ‘ ‘ ‘ ‘ ‘ ‘ ‘ Total No. of Pages : 02
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Total No. of Questions : 18B.Tech.(BT) (2012 to 2017) (Sem.-4)
CELL & MOLECULAR BIOLOGY
Subject Code : BTBT-404
M.Code : 55087
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Time : 3 Hrs. Max. Marks : 60INSTRUCTION TO CANDIDATES :
- SECTION-A is COMPULSORY consisting of TEN questions carrying TWO marks each.
- SECTION-B contains FIVE questions carrying FIVE marks each and students have to attempt any FOUR questions.
- SECTION-C contains THREE questions carrying TEN marks each and students have to attempt any TWO questions.
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SECTION-A
Answer briefly :
- What are the properties of DNA polymerases?
- Write the termination codons. What is the importance of termination codon?
- What is the role of sigma factor in bacterial transcription?
- Differentiate between euchromatin and heterochromatin.
- What are the enzymes and proteins involved in the initiation of DNA replication in prokaryotes?
- What is the importance of DNA methylation in E. coli genome replication and repair?
- Describe excision based repair system.
- Explain the semi-conservative replication of DNA.
- What is a promoter?
- Define endocytosis.
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1|M-55087 (52)-804
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Firstranker's choiceSECTION-B
- Using suitable diagrams describe Okazaki fragments. How are Okazaki fragments joined in eukaryotes and prokaryotes.
- Define polymerization rate, processivity and proof reading activity of DNA polymerase.
- Explain the different DNA repair mechanisms.
- Write short notes on any two :
- Telomerase and its significance
- Cot curve and its significance
- Structure and function of Microtubules
- Properties of Genetic code
- How are bacterial genomes different from genomes of multicellular eukaryotes?
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SECTION-C
- What is the principle of PCR? Describe the steps involved in PCR and the importance of various parameters.
- Differentiate between Meiosis and Mitosis and describe the process of meiosis during oogenesis in humans.
- Give the different phases of cell cycle and write a note on cell cycle check points.
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NOTE : Disclosure of Identity by writing Mobile No. or Making of passing request on any page of Answer Sheet will lead to UMC against the Student.
2|M-55087 (52)-804
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