Download PTU B-Tech Bio Technology 2020 Dec 6th Sem 71075 Computational Biology Question Paper

Download PTU (I.K.Gujral Punjab Technical University (IKGPTU)) B-Tech (Bachelor of Technology) BT-Bio Technology 2020 December 6th Sem 71075 Computational Biology Previous Question Paper

Roll No.
Total No. of Pages : 02
Total No. of Questions : 18
B.Tech. (BT) (2012 to 2017) (Sem.?6)
COMPUT ATIONAL BIOLOGY
Subject Code : BTBT-604
M.Code : 71075
Time : 3 Hrs. Max. Marks : 60
INST RUCT ION TO CANDIDAT ES :
1 .
SECT ION-A is COMPULSORY cons is ting of TEN questions carrying TWO marks
each.
2 .
SECT ION-B c ontains F IVE questions c arrying FIVE marks eac h and s tud ents
have to atte mpt any FOUR q ues tions.
3 .
SECT ION-C contains THREE questions carrying T EN marks e ach and s tudents
have to atte mpt any T WO questio ns.
SECTION-A
Write briefly :
1.
Radiation hybrid mapping
2.
Eulerian cycle
3.
AMBER
4.
MMDB
5.
Gene Hunting
6.
Optical maps
7.
Restriction mapping tool
8.
Application of Lander-waterman in bioinformatics
9.
Fuzzy Logic
10. ADME
1 | M-71075
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SECTION-B
11. Write the different features of KEGG database.
12. Explain the hidden Markov Model.
13. Write the important of docking in drug design. Differentiate between rigid and flexible
docking.
14. Write the important steps required in finding target template to model the three
dimensional structural of protein based on homology modeling approach.
15. Write a perl programme which can be used to convert any sequence fromat to GenBank
sequence format.
SECTION-C
16. Explain the concepts of evolutionary computing. With example, write the application of
evolutionary computing in bioinformatics.
17. Describe different bioinformatics methods of gene prediction? How prokaryotic gene
prediction tool is different from eukaryotic gene prediction tool?
18. Explain DNA double and partial digest. What are the problems encountered during these
digestion of DNA? Write solutions to solve the double and partial digest problem.
NOTE : Disclosure of identity by writing mobile number or making passing request on any
page of Answer sheet will lead to UMC case against the Student.
2 | M-71075
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