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Roll No.
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Total No. of Questions : 24
Total No. of Pages : 02
B.Pharma (2012 to 2016) (Sem.-5)
PHARMACEUTICS-VII
(Biopharmaceutics & Pharmacokinetics)
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Subject Code : BPHM-505
M.Code: 70431
Time: 3 Hrs.
Max. Marks : 80
INSTRUCTIONS TO CANDIDATES :
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- SECTION-A is COMPULSORY consisting of FIFTEEN questions carrying TWO marks each.
- SECTION-B contains FIVE questions carrying FIVE marks each and students have to attempt any FOUR questions.
- SECTION-C contains FOUR questions carrying TEN marks each and students have to attempt any THREE questions.
SECTION-A
Answer briefly :
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- Define Relative Bioavailability.
- What is meant Dosage Regimen?
- Differentiate between drug excretion and elimination.
- What is meant by wash out period?
- Define Volume of Distribution.
- How is Bioavailability related to volume of distribution?
- Define One Compartment Model.
- Write the equation for first order drug elimination kinetics.
- What is MRT and how is it calculated?
- Give examples of plasma proteins that contribute to drug binding.
- At steady state what is relation between Ka and Ke?
- What is First Pass Effect?
- Define Tmax.
- Write Handerson-Hasselbalch equation.
- Define Facilitated Transport.
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SECTION-B
- What are Non-compartment models?
- What is meant by biopharmaceutics? Enumerate the factors that need to be considered during biopharmaceutical studies.
- Write a note on active transport of drugs in body with suitable examples.
- What are the reasons for instability of drugs in GIT?
- What are regulatory requirements to conduct bioequivalent studies?
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SECTION-C
- Discuss method of residual for calculation of absorption rate constant.
- Discuss various factors affecting the volume of distribution of drugs. Also explain its role in the action of a drug.
- Elaborate upon the significance of plasma drug concentration measurement.
- Discuss briefly the methods used for evaluating in vitro-in vivo correlation.
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NOTE : Disclosure of Identity by writing Mobile No. or Making of passing request on any page of Answer Sheet will lead to UMC against the Student.
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This download link is referred from the post: PTU B.Pharma 5th Semester Last 10 Years 2011-2021 Previous Question Papers|| Punjab Technical University