Download PTU B.Pharma 2020 Dec 5th Sem 70431 Pharmaceutics Vii (Biopharmaceutics And Pharmacokinetics) Question Paper

Download PTU I. K. Gujral Punjab Technical University (IKGPTU) B.Pharma (Bachelor of Pharmacy) 2020 December 5th Sem 70431 Pharmaceutics Vii (Biopharmaceutics And Pharmacokinetics) Previous Question Paper

Roll No.
Total No. of Pages : 02
Total No. of Questions : 24
B.Pharma (2012 to 2016) (Sem.?5)
PHARMACEUTICS-VII
(Biopharmaceutics & Pharmacokinetics)
Subject Code : BPHM-505
M.Code : 70431
Time : 3 Hrs. Max. Marks : 80
INST RUCT IONS T O CANDIDAT ES :
1 .
SECT ION-A is C OMPULSORY co nsisting of FIFT EEN questio ns carrying TWO
marks eac h.
2 .
SECT ION-B c ontains F IVE questions c arrying FIVE marks eac h and s tud ents
have to atte mpt any FOUR q ues tions.
3 .
SECT ION-C contains FOUR q uestions carrying T EN marks eac h an d s tud ents
have to atte mpt any T HREE que stions .
SECTION-A
Answer briefly :
1.
Define Relative Bioavailability.
2.
What is meant Dosage Regimen?
3.
Differentiate between drug excretion and elimination.
4.
What is meant by wash out period?
5.
Define Volume of Distribution.
6.
How is Bioavailability related to volume of distribution?
7.
Define One Compartment Model.
8.
Write the equation for first order drug elimination kinetics.
9.
What is MRT and how is it calculated?
10. Give examples of plasma proteins that contribute to drug binding.
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11. At steady state what is relation between Ka and Ke?
12. What is First Pass Effect?
13. Define Tmax.
14. Write Handerson-Hasselbach equation.
15. Define Facilitated Transport.
SECTION-B
16. What are Non-compartment models?
17. What is meant by biopharmaceutics? Enumerate the factors that need to be considered
during biopharmaceutical studies.
18. Write a note on active transport of drugs in body with suitable examples.
19. What are the reasons for instability of drugs in GIT?
20. What are regulatory requirements to conduct bio equivalent studies?
SECTION-C
21. Discuss method of residual for calculation of absorption rate constant.
22. Discuss various factors affecting the volume of distribution of drugs. Also explain its role
in the pharmacokinetics of a drug.
23. Elaborate upon the significance of plasma drug concentration measurement.
24. Discuss briefly the methods used for evaluating in vitro-in vivo correlation .
NOTE : Disclosure of Identity by writing Mobile No. or Making of passing request on any
page of Answer Sheet will lead to UMC against the Student.
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