Download PTU I. K. Gujral Punjab Technical University (IKGPTU) B.Pharma (Bachelor of Pharmacy) 2020 December 6th Sem 71033 Pharmaceutical Chemistry Vi (Medicinal Chemistry I) Previous Question Paper
Total No. of Pages : 02
Total No. of Questions : 24
B.Pharma (2012 to 2016) (Sem.?6)
PHARMACEUTICAL CHEMISTRY-VI
(Medicinal Chemistry-I)
Subject Code : BPHM-601
M.Code : 71033
Time : 3 Hrs. Max. Marks : 80
INST RUCT IONS T O CANDIDAT ES :
1 .
SECT ION-A is C OMPULSORY co nsisting of FIFT EEN questio ns carrying TWO
marks eac h.
2 .
SECT ION-B c ontains F IVE questions c arrying FIVE marks eac h and s tud ents
have to atte mpt any FOUR q ues tions.
3 .
SECT ION-C contains FOUR q uestions carrying T EN marks eac h an d s tud ents
have to atte mpt any T HREE que stions .
SECTION-A
Explain the terms :
1.
What do you mean by term lead?
2.
Classification of NSAIDS.
3.
MOA of Apormorphine.
4.
Water soluble Vitamins.
5.
Give the structure of Nifedipine and Prazosin.
6.
Bioisosterism.
7.
Name two irreversible gastric proton pump inhibitors.
8.
Give the therapeutic class and structure of Chloropheniramine.
9.
Name and give MOA of drug used as analgesic.
10. Storage of acetyl choline.
11. Classification of Prostaglandins.
1 | M - 7 1 0 3 3
( S 4 ) - 9 6 9
12. MOA of antispasmodic drugs.
13. Biosynthesis of Prostaglandins.
14. Metabolism of catecholamines.
15. Use and MOA of Sodium Cromoglycate.
SECTION-B
16. Mechanism and significance of bioisosterism.
17. Explain the SAR and mechanism of action of Antiparkinson's disease.
18. Enumerate the biosynthesis of noradrenaline.
19. Short notes on cholinergic receptors.
20. Adrenergic neurotransmitters.
SECTION-C
21. What do understand by Lead? Explain the various methods to obtain the lead along with its
optimization.
22. Discuss in detail about the different types of drug receptor interactions.
23. Classify Neuromuscular blocking agents with examples. Give the mode of action and
synthesis of one drug form two different classes.
24. Discuss the SAR of NSAIDS in detail with example from each category. Give the synthesis
of any one drug.
NOTE : Disclosure of identity by writing mobile number or making passing request on any
page of Answer sheet will lead to UMC against the Student.
2 | M - 7 1 0 3 3
( S 4 ) - 9 6 9
This post was last modified on 14 February 2021