Roll No.
Total No. of Questions : 22
B.Pharma (2017 Batch)
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Total No. of Pages : 02
(Sem.-6)
PHARMACEUTICAL BIOTECHNOLOGY-THEORY
Subject Code : BP-605T
M.Code: 77990
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Time: 3 Hrs.
Max. Marks : 75
INSTRUCTIONS TO CANDIDATES :
- SECTION-A is COMPULSORY consisting of TEN questions carrying TWO marks each.
- SECTION-B contains THREE questions carrying TEN marks each and student has to attempt any TWO questions.
- SECTION-C contains NINE questions carrying FIVE marks each and student has to attempt any SEVEN questions.
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SECTION-A
Explain the following terms in brief :
- Genetic engineering
- Biosensors
- Recombinant DNA technology
- Cloning vectors
- Hypersensitivity
- Immunoglobulins
- Microbial transduction
- Southern blotting
- Penicillins
- Human plasma
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SECTION-B
- Define Enzyme Biotechnology. Give methods of enzyme immobilization and their applications with reference to Pharmaceutical sciences.
- Explain principle and technique of recombinant DNA technology and its applications for the production of Hepatitis vaccine and Insulin hormone.
- Explain principle, methodology and applications of ELISA. Also provide a well illustrated diagram showing different types of ELISA technique.
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SECTION-C
- Explain method of production and usage of amylases and Penicillinases for pharmaceutical product development.
- Draw well illustrated diagram showing different parts and working of a Biosensor. Briefly explain potential applications of Biosensors in Pharmaceutical sciences.
- What are Cloning Vectors? Highlight their features and applications in r-DNA technology.
- Explain briefly the structure and functions of Complex (MHC). Histocompatibility
- Differentiate between cellular and humoral immune responses using supporting examples.
- Define the term Mutagenesis. Explain different types of mutations and utility of mutant organisms in Pharmaceutical industries.
- Draw well labeled diagrams showing genetic features of plasmids and transposons. Compare genetic features of prokaryotes and eukaryotes using suitable examples.
- Provide detailed note on design and working of a large scale fermenter. What are general requirements and methods used in fermentation technology?
- How do you collect, process and store whole human blood?
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NOTE: Disclosure of Identity by writing Mobile No. or Making of passing request on any page of Answer Sheet will lead to UMC against the Student.
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This download link is referred from the post: PTU B.Pharma 6th Semester Last 10 Years 2011-2021 Previous Question Papers|| Punjab Technical University