Download PTU M.Pharma 2020 Dec 2nd Sem 74944 Pharmacological And Toxicological Screening Methods Ii Question Paper

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M.Pharmacy (Pharmacology) (2017 & Onwards) (Sem.-2)

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PHARMACOLOGICAL & TOXICOLOGICAL SCREENING METHODS-II

Subject Code : MPL-202T

M.Code: 74944

Time: 3 Hrs.

Max. Marks: 75

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INSTRUCTIONS TO CANDIDATES:

1. Attempt any FIVE questions out of SIX questions.
2. Each question carries FIFTEEN marks.

1. Write a detailed note on OECD principles of GLP.
2. Explain safety pharmacological studies? Describe in tier 1 and 2 studies in detail.

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3. Explain :
   1. Schedule Y.
   2. Toxicology and its types.
   3. IND enabling studies.
4. How will you carry out acute, sub-acute and chronic dermal toxicity studies as per OECD guidelines?

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5. Write a detailed note on male reproductive toxicity studies and Genotoxicity studies.
6. Write a short note on :
   1. Toxicokinetic evaluation and their importance in preclinical studies.
   2. Discuss the alternative methods to animal toxicity testing.

NOTE : Disclosure of Identity by writing Mobile No. or Making of passing request on any page of Answer Sheet will lead to UMC against the Student.

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