Download DNB 2019 June MEDICAL ONCOLOGY MEDICAL ONCOLOGY PAPER 2 Question Paper

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FINAL EXAM

JUNE 2019

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MEDICAL ONCOLOGY

PAPER-II

Time: 3 hours

Max. Marks: 100

Important Instructions:

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• Attempt all questions in order.
• Each question carries 10 marks.
• Read the question carefully and answer to the point neatly and legibly.
• Do not leave any blank pages between two answers.
• Indicate the question number correctly for the answer in the margin space.

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• Answer all the parts of a single question together.
• Start the answer to a question on a fresh page or leave adequate space between two answers.
• Draw table/diagrams/flowcharts wherever appropriate.

Write short notes on:

1. a) Causes of malignant spinal cord compression (MSCC). 3+3+4
   

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   b) Grading the MSCC.
   c) Management of MSCC.
2. a) Gene expression profile. 2+4+4
   b) What are the tests available for breast cancer gene expression profile?
   c) Use of gene expression profile results in breast cancer management.

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3. a) Staging of non-small cell lung cancer (NSCLC) 4+3+3 according to 8th Edition Lung Cancer Stage Classification.
   b) Role of mutation analysis in treatment of NSCLC.
   c) Consolidation treatment after definitive concurrent chemo-radiation in stage II NSCLC.
4. a) Role of PET CT scan in lymphomas. 4+3+3
   b) Limitations of PET CT use in clinical practice.
   

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   c) PET response adopted treatment in Hodgkin's lymphoma.
5. a) WHO Classification of neuroendocrine tumours of pancreas. 3+4+3
   b) Management of advanced pancreatic neuroendocrine tumours.
   c) Peptide receptor radiotherapy.
6. a) Gleason grading in adenocarcinoma prostate. 3+3+4
   

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   b) Role of PSA in screening and follow up of prostate cancer.
   c) Enumerate anti-androgen therapies in carcinoma prostate.
7. Role of cytoreductive nephrectomy in metastatic renal cell carcinoma. 3+4+3
   Role of adjuvant treatment in clear cell renal cell carcinoma. 3+4+3
   Risk scoring systems and their use in metastatic renal cell carcinoma. 3+4+3

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8. Explain the methodology of Real time polymerase chain reaction (RT PCR). 3+4+3
   Monitoring of response in CML treatment
   Criteria for accelerated phase and blast crisis in CML.
9. Etiological factors of Hepatocellular Carcinoma (HCC).
   Diagnosis and staging of HCC.
   

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   Indications of allogenic liver transplantation in HCC.
10. Enumerate various types of neck dissections in squamous cell carcinoma of head and neck.
    Role of neo-adjuvant chemotherapy in oro-pharyngeal cancer.
    Rehabilitation after laryngectomy.

POSSESSION/USE OF CELL PHONES OR ANY SUCH ELECTRONIC GADGETS IS NOT PERMITTED INSIDE THE EXAMINATION HALL.

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