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FINAL EXAM
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JUNE 2019Time: 3 hours
Max. Marks: 100
Important Instructions:
- Attempt all questions in order.
- Each question carries 10 marks.
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PATHOLOGY
PAPER-I
PATH/J/19/32/1
- Read the question carefully and answer to the point neatly and legibly.
- Do not leave any blank pages between two answers.
- Indicate the question number correctly for the answer in the margin space.
- Answer all the parts of a single question together.
- Start the answer to a question on a fresh page or leave adequate space between two answers.
- Draw table/diagrams/flowcharts wherever appropriate.
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Write short notes on:
- Define apoptosis. Discuss the biochemical features and pathogenesis of apoptosis. 1+(3+6)
- A 25-year-old multipara is admitted with severe bleeding and breathlessness after a stillborn baby is delivered by her. Discuss the investigations and pathology behind her condition. 5+5
- a) Gene silencing 5+5
b) Gene expression profiling - a) Classification of leprosy 2+5+3
b) Immunopathology of leprosy
c) Type | reaction - a) Radiation injury. 5+5
b) Basement membrane role in disease. - a) Tissue Microarray. 5+5
b) Pathogenesis of steatosis - a) Endothelial leukocyte interaction in acute inflammation. 5+5
b) Signaling mechanism in cell growth. - a) Preanalytical variables in histopathology laboratory. 5+5
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b) Protein misfolding diseases. - a) Pathophysiology of autoimmune diseases. 5+5
b) APLA syndrome - a) Cytogenetic disorders involving sex chromosomes 5+5
b) Mosaicism
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POSSESSION/USE OF CELL PHONES OR ANY SUCH ELECTRONIC GADGETS IS NOT PERMITTED INSIDE THE EXAMINATION HALL.
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