Download DNB 2019 Dec 2019 Dec BIOCHEMISTRY PAPER II Question Paper

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FINAL EXAM

DECEMBER 2019

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BIOCHEMISTRY

PAPER-II

Time: 3 hours BCHEM/D/19/03/l1 Max. Marks:100

Important Instructions:

• Attempt all questions in order.

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• Each question carries 10 marks.
• Read the question carefully and answer to the point neatly and legibly.
• Do not leave any blank pages between two answers.
• Indicate the question number correctly for the answer in the margin space.
• Answer all the parts of a single question together.

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• Start the answer to a question on a fresh page or leave adequate space between two answers.
• Draw table/diagrams/flowcharts wherever appropriate.

Write short notes on:

1. a) Energy value of foods. 5+5
   b) Enumerate two physiological and three pathological conditions which affect the Basal Metabolic Rate.

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2. Discuss Obesity and how it can be managed through low calorie diet 4+6 and exercise.
3. a) Disorders associated with altered G-Protein activity. 5+5
   b) Disorders associated with deficiency and excess of Growth hormone.
4. Enlist two 5 Carbon, one 7 Carbon, one 4 Carbon and one 6 Carbon 6+2+2 Sugar derivatives formed in the pentose phosphate pathway. Which of the above derivatives are used for nucleic acid synthesis? And which metabolite(s) is/are shunted to glycolytic pathway?
5. Sketch the chronology of events which food starch undergoes till it is 10 used for the synthesis of ATP in inner mitochondrial membrane.

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6. Describe the functions of: 3+3+4
   a) Arachidonic acid.
   b) Slow Reacting Substances-A.
   c) Phospholipase A2 in lipid metabolism.
7. How do calcitonin and calcitriol maintain the homeostasis of calcium? 6+(2+2) Add a note on Calcium in diet and osteoporosis.

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8. Why folic acid and vitamin B12 are given together in the treatment of 5+5 macrocytic megaloblastic anemia? Explain the absorption of extrinsic factor of Castle.
9. Describe the biosynthesis of serotonin. Explain malignant carcinoid 5+5 syndrome, and its clinical & biochemical manifestations.
10. a) Lohmann’s reaction. 5+5
    b) Substrate level phosphorylation.

POSSESSION/USE OF CELL PHONES OR ANY SUCH ELECTRONIC GADGETS IS NOT PERMITTED INSIDE THE EXAMINATION HALL.

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