FINAL EXAM
DECEMBER 2019
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PHARMACOLOGY
PAPER-III
Time: 3 hours PHARM/D/19/34/111 Max. Marks:100
Important Instructions:
- Attempt all questions in order.
- Each question carries 10 marks.
- Read the question carefully and answer to the point neatly and legibly.
- Do not leave any blank pages between two answers.
- Indicate the question number correctly for the answer in the margin space.
- Answer all the parts of a single question together.
- Start the answer to a question on a fresh page or leave adequate space between two answers.
- Draw table/diagrams/flowcharts wherever appropriate.
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Write short notes on:
1. Give an outline of experimental methods for evaluating antiepileptic drugs. 10
2. Discuss in details the pharmacological screening of a natural product with potential antihypertensive activity. How would you locate the site of antihypertensive action? 8+2
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3. How would you design the toxicity studies for new synthetic compounds with anti-inflammatory activity? 10
4. Importance of biostatistics in medical experimentations. 10
5. Discuss the considerations and approach to calculate minimum sample size for clinical trial of a new drug in comparison with standard therapy. 10
6. Why the measures of Confidence Interval (Cl) should be added with p-value during writing result of a clinical research? 10
7. a) Attributable risk reduction. 5+5
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b) Multivariate regression analysis.8. Explain with examples “Safety Pharmacology” studies in new drug development. 10
9. Briefly outline the laboratory animal facility as per CPCSEA. 10
10. Write a commentary on per-protocol vis-a-vis intention to treat analysis. 10
POSSESSION/USE OF CELL PHONES IS NOT PERMITTED INSIDE THE EXAMINATION HALL.
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This download link is referred from the post: DNB 2019 Dec Previous Question Papers-(Diplomate of National Board) Under NBE
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