Download DNB 2019 Dec 2019 Dec PHYSIOLOGY PAPER I Question Paper

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FINAL EXAM

DECEMBER 2019

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PHYSIOLOGY

PAPER-I

Time: 3 Hours

Max. Marks: 100

Important Instructions:

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1. Attempt all questions in order.
2. Each question carries 10 marks.
3. Read the question carefully and answer to the point neatly and legibly.
4. Do not leave any blank pages between two answers.
5. Indicate the question number correctly for the answer in the margin space.

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6. Answer all the parts of a single question together.
7. Start the answer to a question on a fresh page or leave adequate space between two answers.
8. Draw table/diagrams/flowcharts, wherever appropriate.

Write short notes on:

1. In the context of ventricular myocardial muscle:
   1. State different phases of action potential and their ionic mechanism. (5)

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   2. Define refractory period, its mechanism and importance. (5)
2. 1. Describe different mechanisms by which cells internalize extracellular material. (6)
   2. Add a note on receptor mediated endocytosis. (4)

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3. 1. Explain the terms transcription and translation in gene expression. (3)
   2. Give detailed account of transcription factors in terms of types, function and regulation. (7)
4. 1. Outline the distribution of water in different compartment of the body. (4)
   2. With help of an example, describe the method of estimation of volume of a body fluid compartment. (6)

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5. 1. Compare and contrast excitation contraction coupling in skeletal, cardiac and smooth muscle. (6)
   2. Explain the importance of latch phenomenon. (4)
6. 1. Describe the general properties of G protein coupled receptors. (5)

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   2. Outline the various secondary messengers associated with G protein coupled receptors. (5)
7. 1. Compare and contrast innate immunity and adaptive immunity. (4)
   2. Describe the role of complement proteins in innate immunity. (6)

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8. Explain the role of various organ systems involved in regulation of:
   1. Intravascular volume. (5)
   2. Osmolality of body fluids. (5)
9. Outline the formation of different types of blood cells from a hematopoietic stem cell. Explain the concept of hematopoietic niche. (7+3)
10. Formulate a plan for statistical analysis of quantitative data obtained from three separate groups of subjects (n=50) in a cross-sectional study design. (10)

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POSSESSION/USE OF CELL PHONES OR ANY SUCH ELECTRONIC GADGETS IS NOT PERMITTED INSIDE THE EXAMINATION HALL.