Download DNB 2019 Dec 2019 Dec MEDICAL ONCOLOGY PAPER I Question Paper

Download Diplomate in National Board (DNB) 2019 Dec 2019 Dec MEDICAL ONCOLOGY PAPER I Previous Question Papers

FINAL EXAM NATIONAL BOARD OF EXAMINATIONS
DECEMBER 2019
MEDICAL ONQQLOGY
PAPER-l
Time: 3 hours MED.ONCOlD/19l17ll
Max. Marksz100
Important Instructions:
0 Attempt all questions in order.
Each question carries 10 marks.
Read the question carefully and answer to the point neatly and leglb/y.
Do not leave any blank pages between two answers,
Indicate the question number correctly for the answer in the margin space.
Answer all the parts of a single question together.
Start the answer to a question on a fresh page or leave adequate space between two answers.
Draw table/dlagrems/?owcharts Wherever appropriate.
Write short notes on:
1. a) Clonalevolutiontheory. 3+4+3
b) Cancer stem cell theory.
0) Tumour heterogeneity.
2. a) Enumerate the common carcinogens in tobacco. 2+3+5
b) Which are the common cancers caused by tobacco?
0) Describe in detail carcinogenesis due to tobacco.
3. a) Radiosensitizer. 2+3+2+3
b) Fractionation of radiation therapy and its importance.
0) Image guided radiation therapy (IGRT).
d) Gamma knife.
4. a) Scientific rationale and scope of liquid biopsy in cancer. 3+4+3
b) Clinical application of liquid biopsy in management of solid
tumours.
0) Potential limitation of liquid biopsy.
5. a) What is cancer genetic counselting? 2+2+3+3
b) Enumerate the hereditary cancer syndromes.
0) How do you counsel a 23?year old lady whose mother and elder
sister died of breast cancer?
d) Management of BRCA carrier.
6. a) Phases of cancer drug clinical trials. 3+4+3
b) Importance of informed consent in clinical trials.
0) Role of principal investigator in clinical trials.
7. a) Define oligometastatic disease. 2+4+4 :
b) Role of circulating tumour cells as a predictor of metastatic ?
disease. '
c) Management of oligometastatic breast cancer.
P.T.O
-1-
l?OSSESS/ON/USE OF CELL PHONES OR A N Y S UC l'l ELECTRONIC GADGETS IS NOT PERMITTED INSIDE THE
lj'X/l MINA 'I'ION I [A LL

FINAL EXAM
DECEMBER 2019
8. a)
b)
C)
9 a)
b)
C)
d)
10. a)
NATIONAL BOARD OF EXAMINATIONS
MEDICAL ONCOLOGY
PAPER-I
What is molecular tumour marker? 2+4+4
Molecular tumour board.
Predictive biomarkers for checkpoint inhibitor?based
immunotherapy.
Survival analysis in cancer. 3+2+3+2
p?value.
Forest plot and its interpretation.
Meta?analysis.
Kinases and cancer. 2+4+4
Kinase amplifications as diagnostic molecular marker in cancer.
Kinase targeted therapy in various cancers.
**~k******
-2-
POSSESSlON/l/SE ()l? C 1.5LL PHONES OR A N Y S UCH ELECTRONIC GA DGETS [S N OT PERM] 77151) INSIDE THE
EX/l MINA '1 'ION HA LL.