DNB 2019 Dec Previous Question Papers-(Diplomate of National Board) Under NBE
NATIONAL BOARD OF EXAMINATIONS
DECEMBER 2019
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Time: 3 Hours
MICROBIOLOGY
PAPER-I
Max. Marks: 100
Important Instructions:
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- Attempt all questions in order.
- Each question carries 10 marks.
- Read the question carefully and answer to the point neatly and legibly.
- Do not leave any blank pages between two answers.
- Indicate the question number correctly for the answer in the margin space.
- Answer all the parts of a single question together.
- Start the answer to a question on a fresh page or leave adequate space between two answers.
- Draw table/diagrams/flowcharts, wherever appropriate.
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Write short notes on:
- Define biofilms. Describe their role in bacterial pathogenesis and various methods of biofilm detection. (2+4+4)
- What is quorum sensing? Discuss in detail about its role in bacterial virulence. (4+6)
- Enumerate nucleic acid amplification techniques used in diagnostic microbiology. Discuss in detail about nucleic acid sequence based amplification (NASBA) and its applications. (3+(5+2))
- What is sterilization? Discuss principle of plasma sterilizers. Write its advantages as well as uses. (3+3+(2+2))
- Describe in detail methods of HLA typing. Discuss merits and demerits of each method and also add a note on HLA typing for the next-generation sequencing. (5+3+2)
- Describe monoclonal antibodies. Discuss emerging trends and newer developments in monoclonal antibodies. (4+6)
- Enumerate major Hospital Acquired Infections (HAI). Discuss in detail about laboratory diagnosis of Ventilator Associated Pneumonia (VAP). Add a note on surveillance of VAP in a hospital setting. (2+4+4)
- Enumerate potential pathogens found and/or transmitted through milk. Describe various methods used for the assessment of bacterial contamination of milk. (4+6)
- Define ‘Pathogenicity Islands’ and their role in bacterial pathogenesis with suitable examples. (4+6)
- Discuss the role of microbiota in health and diseases. (10)
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