PHARMACOLOGY
PAPER-III
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PHARMA/D/17/34/11
Time: 3 hours
Max. Marks: 100
Attempt all questions in order.
Each question carries 10 marks.
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Read the question carefully and answer to the point neatly and legibly.
Do not leave any blank pages between two answers.
Indicate the question number correctly for the answer in the margin space
Answer all the parts of a single question together.
Start the answer to a question on a fresh page or leave adequate space between two answers.
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Draw table/diagrams/flowcharts wherever appropriate.
Write short notes on:
- a) Chi Square test and its application in pharmacological research (5+5)
b) Principle and method of determinants of sample size calculations for clinical trials - a) Current strategies to overcome antimicrobial resistance (5+5)
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b) Pharmacotherapy of osteoporosis - a) Mention targeted cancer therapies giving examples. (5+5)
b) Mechanism of action and potential uses of bevacizumab. - a) Enumerate current drugs used for leishmaniasis with their merits and demerits (5+5)
b) Mechanism of action and adverse reaction of miltefosine - a) Enumerate anti-malarial drugs used as radical curatives and gametocytocidal (4+6)
b) Pharmacotherapy of chloroquine resistant malaria - a) What are the differences between conventional and atypical anti-psychotic agents? (5+5)
b) Enumerate drugs with their mechanism of action for cognitive deterioration. - a) Write the difference between succinylcholine and d-tubocurarine (5+5)
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b) Pharmacotherapy of migraine - a) Enumerate various class of drugs used in cardiac arrhythmias. (5+5)
b) Clinical pharmacology, adverse reactions and therapeutic uses of sotalol - a) Discuss pharmacotherapy of multi-drug resistant tuberculosis. (5+5)
b) Outline mechanisms and adverse effect of drugs used in leprosy. - a) Rational antihypertensive drug combinations. (5+5)
b) Role of vasopeptidase inhibitor in cardiac failure.
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POSSESSION/USE OF CELL PHONES OR ANY SUCH ELECTRONIC GADGETS IS NOT PERMITTED INSIDE THE EXAMINATION HALL
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