Download DNB 2017 Dec BIOCHEM BIOCHEM PAPER IV Question Paper

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Final Exam

DECEMBER 2017

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BIOCHEMISTRY

PAPER - IV

Time : 3 hours BIO/D/17/03/IV Max. Marks : 100

Important instructions:

• Attempt all questions in order.

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• Each question carries 10 marks.
• Read the question carefully and answer to the point neatly and legibly.
• Do not leave any blank pages between two answers.
• Indicate the question number correctly for the answer in the margin space.
• Answer all the parts of a single question together.

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• Start the answer to a question on a fresh page or leave adequate space between two answers.
• Draw table/diagrams/flowcharts wherever appropriate.

Write short notes on:

1. Types of stem cells and their therapeutic potential. 10
2. What is gene therapy? How does it work? Explain gene transfer vehicles. 2+4+4

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3. High Pressure /Performance Liquid Chromatography (HPLC) and its advantages. 6+4
4. Molecular cloning and its applications. 6+4
5. Compare and contrast methods /applications of Radio Immunoassay and enzyme linked immunoassay. 10
6. a) DNA fingerprinting 5+5
   b) RT-PCR (Reverse Transcriptase — Polymerase Chain Reaction)

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7. a) Flow cytometry 5+5
   b) Mass spectrometry
8. a) SnRNAs 5+5
   b) Micro RNAs
9. a) HIV vaccine 5+5
   

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   b) Anti-obesity vaccine
10. a) Micro array technique 5+5
    b) Antisense therapy

POSSESSION/USE OF CELL PHONES OR ANY SUCH ELECTRONIC GADGETS IS NOT PERMITTED INSIDE THE EXAMINATION HALL.

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