DECEMBER 2017
MEDICAL ONCOLOGY
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PAPER — II
Time : 3 hours MED.ONCO./D/A7/17/I Max. Marks :100
Important instructions:
- Attempt all questions in order.
- Each question carries 10 marks.
- Read the question carefully and answer to the point neatly and legibly.
- Do not leave any blank pages between two answers.
- Indicate the question number correctly for the answer in the margin space.
- Answer all the parts of a single question together.
- Start the answer to a question on a fresh page or leave adequate space between two answers.
- Draw table/diagrams/flowcharts wherever appropriate.
- POSSESSION/USE OF CELL PHONES OR ANY SUCH ELECTRONIC GADGETS IS NOT PERMITTED INSIDE THE EXAMINATION HALL.
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1. Write short notes on:
- What is metronomics in cancer care? (2+3+5)
- Mechanisms proposed for metronomic therapy.
- Mention randomized trial based inference for and against use of metronomic therapy in refractory cancers.
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2. With respect to oral cancer, describe: (3+3+4)
- Epidemiology
- Role of viral etiology
- Role of targeted therapy
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3. (4+3+3)
- Epidemiology of gall bladder cancer in India
- Staging of gall bladder-cancer.
- Role of chemotherapy in unresectable gall bladder cancer
4. (4+6)
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- Diagnosis of pontine glioma
- Medical management of pontine glioma including targeted therapy
5. (5+5)
- What are the domains of quality of life assessment?
- Mention the tools for assessment of quality of life.
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6. (4+6)
- Predictors of graft versus host disease in haploidentical transplant
- Pros and cons of cord stem cell transplant versus haploidentical transplant for malignancies.
7. (4+3+3)
- How is a biosimilar molecule different from a generic molecule?
- What are the trial requirement for a biosimilar agent in India?
- What is a phase IV clinical trial?
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DECEMBER 2017
MEDICAL ONCOLOGY
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PAPER — II
8. (3+2+2+3)
- Which cases of breast and ovarian cancer you would send for genetic counseling?
- What diagnostic tests would be performed for detecting hereditary breast / ovarian cancer syndrome?
- How would you plan the follow up of these patients?
- What is the supporting evidence for prophylactic mastectomy in this setting?
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9. (4+3+3)
- Staging system of neuroblastoma.
- How is stage IVS neuroblastoma different from stage IV neuroblastoma.
- Targeted therapy for neuroblastoma.
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10. (4+3+3)
- Role of viral and bacterial infections in causing lymphoma.
- Treatment of an organism related lymphoma- Explain with example.
- Setting of lymphoma where only radiotherapy is used.
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This download link is referred from the post: DNB 2017 Dec Previous Question Papers-(Diplomate of National Board) Under NBE
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