Download DNB 2016 Dec IMMUNO HEMATOLOGY AND TRANSFUSION MEDICINE PAPER 2 Question Paper

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FINAL EXAM NATIONAL BOARD OF EXAMINATIONS

DECEMBER 2016

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IMMUNO-HEMATOLOGY & TRANSFUSION MEDICINE

PAPER — II

IHTM/D/16/15/1

Time : 3 hours Max. Marks :100

Important instructions:

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• Attempt all questions in order.
• Each question carries 10 marks.
• Read the question carefully and answer to the point neatly and legibly.
• Do not leave any blank pages between two answers.
• Indicate the question number correctly for the answer in the margin space.

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• Answer all the parts of a single question together.
• Start the answer to a question on a fresh page or leave adequate space between two answers.
• Draw table/diagrams/flowcharts wherever appropriate.

Write short notes on:

1. Detail out the important component of computer crossmatch. (6+4)

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2. Steps to validate the software for computer crossmatch. (3+3+4)
3. Major ABO mismatch allogenic bone marrow transplant. (5+5)
4. Preparation of the bone marrow harvest. (10)
5. Transfusion management. (10)
6. a) HLA crossmatch. (5+5) b) Methods to enhance sensitivity of identifying HLA antibodies.

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7. Advise patient who insists that she has been typed as A RhD positive before in another hospital but has been typed as A RhD negative in your laboratory. (6+4)
8. Advise a 32 year old regular blood donor who has donated blood five weeks ago and wants to donate platelets on this occasion. (6+4)
9. a) A 22 year old medical student has been donating blood once a year for the past 3 years. No problems were encountered previously but the third time the donated unit was found to be anti-HIV reactive. (6+4) b) As the in-charge how will you manage the situation? c) What actions can be taken to prevent re-occurrence?
10. a) TRALI (5+5) b) What is the incidence of TRALI in India and reasons why it is low?
11. a) Stem cell enumeration for harvest. (6+4) b) Stem cell harvest and its quality check.

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12. a) Platelet antigen system. (6+4) b) Post transfusion purpura.
13. a) A 35 year old Bengali labourer comes to donate blood in your blood bank which is in Maharashtra. How will you go about helping him donate blood? (5+5) b) How will you arrange pre & post donation counseling?

POSSESSION / USE OF CELL PHONES IS NOT PERMITTED INSIDE THE HALL.